Evidence map›Paper›PMID 40601285›Full record

ReviewGlycoconjugate journal2025

Progress in research on DDOST dysregulation in related diseases.

Haoan Sun, Chunbao Xie

Abstract readReview
PubMed Publisher
In one paragraph

Review in Glycoconjugate journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Haoan SunSchool of Medicine, University of Electronic Science and Technology of China, Chengdu, Sichuan, China.
Chunbao XieDepartment of Laboratory Medicine and Sichuan Provincial Key Laboratory for Human Disease Gene Study, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, 32, West Section 2, 1 st Ring Road, Chengdu, Sichuan, 610072, China. xiechunbao2008@163.com.

Funding

Sichuan Provincial Science and Technology Support Program 2023YFS0086
6 · The paper itself

Abstract

DDOST is an important subunit of N-glycosylated oligosaccharyltransferase and is closely related to protein N-glycosylation. Some studies have reported that abnormal expression of DDOST is associated with congenital disorders of glycosylation, solid tumours and other diseases. To better understand the progress of research on DDOST in diseases, we herein provide a comprehensive review of the basic functions of DDOST, interactions molecules, DDOST-congenital disorders of glycosylation (DDOST-CDG) and solid tumours. Our review findings will lay a foundation for researchers to better understand the functions of DDOST and to investigate its specific mechanisms of action.

Indexed as

Congenital Disorders of GlycosylationHexosyltransferasesMembrane ProteinsNeoplasmsAnimalsGlycosylationHumansdolichyl-diphosphooligosaccharide - protein glycotransferaseHexosyltransferasesMembrane ProteinsCancerCongenital disorders of glycosylationDDOSTN-glycosylation

Identifiers

PMID40601285

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.