ArticleMethods in molecular biology (Clifton, N.J.)2025
Cre Deleter Mouse Lines for Conditional Knockout of Genes in Testis Cell Types.
Article in Methods in molecular biology (Clifton, N.J.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Spermatogenesis is a highly regulated process in male reproduction that involves interactions among germ cells and multiple somatic cell types culminating in production of sperm in testis. Sertoli cells and different stages of germ cells constantly communicate. Leydig cells in the interstitium produce testosterone. To date, several testis cell-specific Cre deleter mouse lines have been developed. These critical genetic tools allow the investigators to delineate the developmental and cell-specific roles of genes involved in spermatogenesis.
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