Evidence map›Paper›PMID 40601238›Full record

ArticleCanadian journal of anaesthesia = Journal canadien d'anesthesie2025

Perceptions of health care providers involved in organ donation or transplantation on cardiac donation after death by circulatory criteria: a qualitative study.

Kimia Honarmand, Ian Ball, Maureen O Meade, Aimee Sarti, Danielle LeBlanc, John Basmaji, Emilie P Belley-Côté, Michaël Chassé, Frédérick D'Aragon, Gordon Guyatt and 6 more

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Article in Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Kimia HonarmandDivision of Critical Care, Department of Medicine, Mackenzie Health, 3200 Major Mackenzie Dr W, Vaughan, ON, L6A 4Z3, Canada. kimia.honarmand@mackenziehealth.ca.ORCID 0000-0002-7583-1445
Ian BallDepartment of Medicine, Schulich School of Medicine & Dentistry, Western University, London, ON, Canada.
Maureen O MeadeDepartment of Medicine, Faculty of Health Sciences, McMaster University, Hamilton, ON, Canada.
Aimee SartiUniversity of Ottawa, Ottawa, ON, Canada.
Danielle LeBlancDepartment of Medicine, Schulich School of Medicine & Dentistry, Western University, London, ON, Canada.
John BasmajiDepartment of Medicine, Schulich School of Medicine & Dentistry, Western University, London, ON, Canada.
Emilie P Belley-CôtéDepartment of Medicine, Faculty of Health Sciences, McMaster University, Hamilton, ON, Canada.
Michaël ChasséUniversité de Montréal, Montreal, QC, Canada.
Frédérick D'AragonDepartment of Anesthesiology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, QC, Canada.
Gordon GuyattDepartment of Health Research Methods, Evidence, and Impact (HEI), Faculty of Health Sciences, McMaster University, Hamilton, ON, Canada.
Bram RochwergDepartment of Medicine, Faculty of Health Sciences, McMaster University, Hamilton, ON, Canada.
Sam D ShemieMcGill University, Montreal, QC, Canada.
Robert SibbaldDepartment of Family Medicine, Schulich School of Medicine & Dentistry, Western University, London, ON, Canada.
Marat SlessarevDepartment of Medicine, Schulich School of Medicine & Dentistry, Western University, London, ON, Canada.
Mathew J WeissTransplant Québec, Montreal, QC, Canada.
Jeanna Parsons LeighFaculty of Health, Dalhousie University, Halifax, NS, Canada.

Funding

Non-US Government Research Support
6 · The paper itself

Abstract

purposeCardiac donation after death determination by circulatory criteria (DCC) can be performed using either 1) direct procurement and perfusion of ex situ organs or 2) normothermic regional perfusion (NRP). Nevertheless, there are concerns regarding the acceptability and ethics of these procedures, particularly NRP in which the blood supply to the brain is surgically interrupted and circulation in the thorax and abdomen is restored prior to heart retrieval. We aimed to understand the perspectives on cardiac donation following DCC of Canadian clinicians who are involved in donation and transplantation.

methodsWe performed a qualitative descriptive study of 75 clinicians to better understand the perspectives of physicians on cardiac DCC. We purposively sampled clinicians who care for organ donors (N = 51) and those who care for transplant recipients (N = 24) in Canada. We performed thematic analysis to generate themes describing participants' perspectives about cardiac DCC and its implementation in Canada.

resultsWe found that the broad support and interest to implement cardiac DCC among the cohort of clinicians interviewed was tempered by their anticipation that other clinicians, donor families, and the public would be less supportive. Donor clinicians were particularly concerned about potential erosion in public trust in the organ donation system as a whole. Participants identified opportunities to address anticipated challenges, including strategies for education and communication around cardiac DCC, staged/gradual introduction of cardiac DCC, and the option for stakeholders (clinicians, donor families, potential transplant recipients) to opt out of participation in cardiac DCC.

conclusionsIn this qualitative study of clinicians involved in organ donation or transplantation across Canada, we found broad support for cardiac DCC. Nevertheless, we observed several challenges with the implementation of cardiac DCC, particularly concerns of nonsupport by other stakeholders. Participants also identified opportunities to address anticipated barriers.

Indexed as

Attitude of Health PersonnelHealth PersonnelTissue and Organ ProcurementAdultCanadaDeathFemaleHeart TransplantationHumansMaleMiddle AgedQualitative ResearchTissue Donorscritical illnessdeath by circulatory criteria, deceased donorsethicsheart transplantationorgan procurement

Identifiers

PMID40601238

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.