SynthesisJournal of endocrinological investigation2025
Global epidemiology of pheochromocytoma: a systematic review and meta-analysis of observational studies.
Synthesis in Journal of endocrinological investigation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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Who cites it
13 citing papers in PubMed.
- Silent pheochromocytoma presenting as refractory hyperglycemia without classic adrenergic symptoms.JCEM case reports · 2026Article
- Osteoporosis and Skeletal Fragility in non-Metastatic Pheochromocytomas and Paragangliomas: The Adrenergic-Skeletal Axis.Calcified tissue international · 2026Review
- Cardiogenic shock due to pheochromocytoma-induced catecholamine crisis in a young woman.JCEM case reports · 2026Article
- The application of artificial intelligence in adrenal imaging: current state of knowledge, challenges, and future directions.Endocrine connections · 2026Article
- Prediction of postoperative hypoglycemia in patients with pheochromocytoma resection: a retrospective study.BMC surgery · 2026Article
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- Machine Learning Approach for Differentiation of Pheochromocytoma from Adrenocortical Cancer and Non-Functioning Adrenal Adenomas.Life (Basel, Switzerland) · 2026Article
- Pheochromocytoma complicated with acute myocardial infarction and cerebral infarction: a case report.Frontiers in oncology · 2026Article
- Case report: pheochromocytoma presenting as acute ST-segment elevation myocardial infarction without coronary artery abnormalities.Frontiers in endocrinology · 2026Article
- A rare initial presentation of giant pheochromocytoma: a case report of acute pulmonary embolism complicated by catecholamine-induced cardiomyopathy.Frontiers in oncology · 2026Article
- Diagnostic Challenges of Abdominal Tumors Without Typical Imaging Features: From Misdiagnosis of Pancreatic Cystadenoma to Adrenal Pheochromocytoma and the Intraoperative Response.The American journal of case reports · 2025Article
- Bone metastases in pheochromocytomas and paragangliomas: a narrative review of presentation, diagnosis and management.Frontiers in endocrinology · 2025Review
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
objectiveThe aim of this systematic review and meta-analysis of observational studies is to provide an overview of the global epidemiology of pheochromocytomas and to evaluate the quality of study reporting for the identified studies.
methodsTwo bibliographic databases, PubMed and Embase, were searched for studies assessing the epidemiology of pheochromocytoma from inception until December 2024. Original observational studies written in English and reporting pheochromocytoma prevalence and/or incidence for a well-defined geographic area were included. Two reviewers independently screened the retrieved articles for inclusion, extracted relevant data, and carried out the evaluation of the quality of study reporting. A narrative synthesis of the results was provided, along with a meta-analysis of both prevalence and incidence of pheochromocytoma.
resultsA total of 14 studies were included in the systematic review, of which 13 were included in the meta-analysis. The pooled prevalence of pheochromocytoma was 19.8 (95% CI: 9.6-40.8) cases per 1,000,000 individuals, and the incidence rate was 1.9 (95% CI: 1.2-2.6) cases per million person-years. Substantial between-study heterogeneity was observed for both prevalence and incidence rates (I
conclusionsOverall, our systematic review and meta-analysis of observational studies revealed significant between-study heterogeneity of prevalence of pheochromocytoma amounting to around 20 per million individuals. Establishing national registries using standardized diagnostic and clinical parameters, along with well-defined selection and analysis criteria, may provide better insight into the epidemiology and the course of this rare disease.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.