ArticleEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2025
Fecal microbiota transplant as treatment for recurrent urinary tract infections: a proof-of-concept study.
Article in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- The silent pharmacist: Harnessing the gut microbiome to improve therapy in hematologic malignancies.Translational oncology · 2026Review
- Multi-site microbiota crosstalk in the postmenopausal: from dysbiosis mechanisms to precision interventions.Frontiers in microbiology · 2026Review
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Authors and funding
9 authors.
Funding
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Abstract
Recurrent urinary tract infections (rUTIs) are a global problem due to their high prevalence and because are caused by antibiotic-resistant strains. The hypothesis of our study is that a fecal microbiota transplant (FMT) might reduce the presence of uropathogenic E. coli in the intestinal microbiota, thereby leading to a decrease in the rUTIs. The objective of this study was to assess the efficacy of a single FMT intervention for the treatment rUTIs. A total of 22 postmenopausal women received a 3-day course of oral rifaximin to reduce their commensal microbiota, followed by a 2-day washout period, and then an oral FMT using lyophilized fecal capsules equivalent to 100 g of freeze-dried fecal matter from a single certificated fecal donor. The results demonstrated that over a period of six months, there was a 68.1% reduction in urinary infectious episodes, with minimal adverse effects. In addition, eradication of fecal colonization of urinary pathogens that were resistant to multiple antibiotics was achieved. The findings of this pilot study indicate that FMT is a promising and safe alternative for the treatment of rUTIs, particularly those caused by multidrug-resistant bacteria.
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