Evidence map›Paper›PMID 40601158›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2026

Interaction Between Pluripotent Stem Cells and Amniotic Epithelium for the In Vitro Study of Human Embryogenesis.

Daniela Ávila-González, Axel Castro-Abrego, Jonathan Salazar-Alonso, Omar Martínez Alarcon, Alejandro Martinez-Juarez, Anayansi Molina Hernández, Nestor Emmanuel Diaz-Martinez, Wendy Portillo, Nestor Fabián Diaz

Abstract read
PubMed Publisher
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Daniela Ávila-GonzálezDepartamento de Fisiología y Desarrollo Celular, Instituto Nacional de Perinatología, Ciudad de México, Mexico.
Axel Castro-AbregoDepartamento de Fisiología y Desarrollo Celular, Instituto Nacional de Perinatología, Ciudad de México, Mexico.
Jonathan Salazar-AlonsoDepartamento de Fisiología y Desarrollo Celular, Instituto Nacional de Perinatología, Ciudad de México, Mexico.
Omar Martínez AlarconDepartamento de Fisiología y Desarrollo Celular, Instituto Nacional de Perinatología, Ciudad de México, Mexico.
Alejandro Martinez-JuarezDepartamento de Fisiología y Desarrollo Celular, Instituto Nacional de Perinatología, Ciudad de México, Mexico.
Anayansi Molina HernándezDepartamento de Fisiología y Desarrollo Celular, Instituto Nacional de Perinatología, Ciudad de México, Mexico.
Nestor Emmanuel Diaz-MartinezLaboratorio de Reprogramación Celular y Bioingenería de Tejidos, Biotecnología Médica y Farmacéutica, Centro de Investigación y Asistencia en Tecnología y Diseño del Estado de Jalisco, Guadalajara, Mexico.
Wendy PortilloDepartamento de Neurobiología Conductual y Cognitiva, Instituto de Neurobiología, UNAM, Quéretaro, Mexico.
Nestor Fabián DiazDepartamento de Fisiología y Desarrollo Celular, Instituto Nacional de Perinatología, Ciudad de México, Mexico.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During the peri-implantation stage in primate embryos, the epiblast coexists with amniotic epithelium, suggesting a pivotal role for this tissue in embryogenesis. This interaction has attracted considerable interest in developmental biology and regenerative medicine due to its potential influence on embryonic patterning and tissue specification. In this protocol, we examined whether co-culturing human amniotic epithelial cells (hAEC) with human embryonic stem cells (hESC) enhances the latter's capacity for differentiation toward human primordial germ cell-like cells (hPGCLC).

Indexed as

AmnionEmbryonic DevelopmentEpithelial CellsHuman Embryonic Stem CellsPluripotent Stem CellsCell DifferentiationCells, CulturedCoculture TechniquesGerm CellsGerm LayersHumansAmnionEpiblastGerm line inductionHuman primordial germ cells

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.