Evidence map›Paper›PMID 40600800›Full record

ArticleeLife2025

Planar cell polarity coordination in a cnidarian embryo provides clues to animal body axis evolution.

Julie Uveira, Antoine Donati, Marvin Léria, Marion Lechable, François Lahaye, Christine Vesque, Evelyn Houliston, Tsuyoshi Momose

Abstract read
In one paragraph

Article in eLife, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Targeting the cell membrane in established and emerging model organisms.bioRxiv : the preprint server for biology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Julie UveiraSorbonne Université, CNRS, Laboratoire de Biologie du Développement de Villefranche-sur-mer (LBDV- UMR7009), Villefranche-sur-mer, France.
Antoine DonatiSorbonne Université, CNRS UMR7622, INSERM U1156, Institut de Biologie ParisSeine (IBPS)-Developmental Biology Unit, Paris, France.ORCID https://orcid.org/0000-0002-3616-3915
Marvin LériaSorbonne Université, CNRS, Laboratoire de Biologie du Développement de Villefranche-sur-mer (LBDV- UMR7009), Villefranche-sur-mer, France.ORCID https://orcid.org/0009-0006-5287-4123
Marion LechableSorbonne Université, CNRS, Laboratoire de Biologie du Développement de Villefranche-sur-mer (LBDV- UMR7009), Villefranche-sur-mer, France.ORCID https://orcid.org/0009-0000-5307-7608
François LahayeSorbonne Université, CNRS, Laboratoire de Biologie du Développement de Villefranche-sur-mer (LBDV- UMR7009), Villefranche-sur-mer, France.
Christine VesqueSorbonne Université, CNRS UMR7622, INSERM U1156, Institut de Biologie ParisSeine (IBPS)-Developmental Biology Unit, Paris, France.ORCID https://orcid.org/0000-0001-7983-4953
Evelyn HoulistonSorbonne Université, CNRS, Laboratoire de Biologie du Développement de Villefranche-sur-mer (LBDV- UMR7009), Villefranche-sur-mer, France.ORCID https://orcid.org/0000-0001-9264-2585
Tsuyoshi MomoseSorbonne Université, CNRS, Laboratoire de Biologie du Développement de Villefranche-sur-mer (LBDV- UMR7009), Villefranche-sur-mer, France.ORCID https://orcid.org/0000-0002-3806-3408

Funding

Agence Nationale de la Recherche ANR-09-BLAN-0236-01Agence Nationale de la Recherche ANR-17-CE13-0016-01Centre National de la Recherche Scientifique Diversity of Biological MechanismsSorbonne Université SATTSU Réseau André Picard
6 · The paper itself

Abstract

Body axis specification is a crucial event in animal embryogenesis and was an essential evolutionary innovation for founding the animal kingdom. This process involves two distinct components that coordinate to establish the spatial organisation of the embryo: initiation of cascades of regionalised gene expression and orientation of morphogenetic processes such as body elongation. Intense interest in the first component has revealed Wnt/β-catenin signalling as ancestrally responsible for initiating regional gene expression, but the evolutionary origin of oriented morphogenesis has received little attention. Here, by addressing the cell and morphological basis of body axis development in embryos of the cnidarian

Indexed as

Biological EvolutionBody PatterningCell PolarityCnidariaEmbryo, NonmammalianAnimalsGene Expression Regulation, DevelopmentalMorphogenesisWnt3 ProteinWnt Signaling PathwayWnt3 Proteinbasal bodycell biologyclytia hemisphaericadevelopmental biologyevolutionplanar cell polarityWnt

Identifiers

PMID40600800
PMCPMC12221298

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.