Evidence map›Paper›PMID 40600749›Full record

ReviewOncology (Williston Park, N.Y.)2025

Cardio-Oncology Considerations for Breast Cancer: Risk Stratification, Monitoring, and Treatment.

Joseph Wallins, Sara Saravia, Olayiwola Bolaji, Zohaib Shaikh, Anthony Yu

Abstract readReview
In one paragraph

Review in Oncology (Williston Park, N.Y.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Joseph Wallins
Sara Saravia
Olayiwola Bolaji
Zohaib Shaikh
Anthony Yu

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI SELWYN M VICKERS · 1985 to 2026
$347.4M
Intensive Blood Pressure Control During Cardiotoxic Breast Cancer Treatment (PROTECT) TrialR37CA273923 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI Anthony Francis Yu · 2023 to 2026
$2.3M
NCI NIH HHS P30 CA008748NCI NIH HHS R37 CA273923
6 · The paper itself

Abstract

Long-term outcomes of patients with breast cancer have steadily improved due to advances in early detection and cancer therapeutics. Cardiovascular disease (CVD) is a leading cause of non-cancer-related mortality in this population, and this has been attributed to the cardiovascular toxicity of common breast cancer treatments including chemotherapy and radiation as well as shared risk factors between cancer and CVD. Identifying patients at risk of developing treatment-related cardiotoxicities is crucial to inform clinical decisions regarding surveillance, prevention, and management. In this review, we provide a broad overview of the treatment-related cardiotoxicities associated with common breast cancer treatment. We present data on risk-stratification tools for oncologists, including when to refer to a cardiologist, as well as recommendations for cardiovascular testing tailored to individual treatment regimens. Lastly, we review recent trial data on preventive and therapeutic approaches to treatment-related cardiotoxicities, and future directions that may lead to improved cardiovascular outcomes in this population.

Indexed as

Antineoplastic AgentsBreast NeoplasmsCardiotoxicityCardiovascular DiseasesCardio-OncologyFemaleHumansRisk AssessmentRisk FactorsAntineoplastic Agents

Identifiers

PMID40600749
PMCPMC13107980

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.