Evidence map›Paper›PMID 40600703›Full record

ArticlemSphere2025

Household clusters of SARS-CoV-2 Omicron subvariants contemporaneously sequenced from dogs and their owners.

Francisco C Ferreira, Lisa D Auckland, Rachel E Busselman, Edward Davila, Wendy Tang, Ailam Lim, Nathan Sarbo, Hayley D Yaglom, Heather Centner, Heather L Mead and 15 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mSphere, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

Francisco C FerreiraDepartment of Entomology, Texas A&M University, College Station, Texas, USA.ORCID 0000-0002-2034-4121
Lisa D AucklandDepartment of Veterinary Integrative Biosciences, Texas A&M University, College Station, Texas, USA.
Rachel E BusselmanDepartment of Veterinary Integrative Biosciences, Texas A&M University, College Station, Texas, USA.ORCID 0000-0001-6315-5040
Edward DavilaDepartment of Veterinary Integrative Biosciences, Texas A&M University, College Station, Texas, USA.
Wendy TangDepartment of Entomology, Texas A&M University, College Station, Texas, USA.
Ailam LimWisconsin Veterinary Diagnostic Laboratory, UW-Madison, Madison, Wisconsin, USA.ORCID 0000-0003-1546-5401
Nathan SarboTranslational Genomics Research Institute (TGen North), Flagstaff, Arizona, USA.
Hayley D YaglomTranslational Genomics Research Institute (TGen North), Flagstaff, Arizona, USA.ORCID 0000-0003-1961-462X
Heather CentnerTranslational Genomics Research Institute (TGen North), Flagstaff, Arizona, USA.
Heather L MeadTranslational Genomics Research Institute (TGen North), Flagstaff, Arizona, USA.ORCID 0000-0002-5680-0758
Ying TaoCenters for Disease Control and Prevention (CDC), Atlanta, Georgia, USA.
Juan CastroEagle Global Scientific, Atlanta, Georgia, USA.
Yan LiCenters for Disease Control and Prevention (CDC), Atlanta, Georgia, USA.
Jing ZhangCenters for Disease Control and Prevention (CDC), Atlanta, Georgia, USA.
Haibin WangIHRC Inc., Atlanta, Georgia, USA.
Lakshmi MalapatiThe St. John Group, LLC, Atlanta, Georgia, USA.
Peter CookCenters for Disease Control and Prevention (CDC), Atlanta, Georgia, USA.ORCID 0000-0002-2058-5646
Adam RetchlessCenters for Disease Control and Prevention (CDC), Atlanta, Georgia, USA.ORCID 0000-0001-7185-591X
Suxiang TongCenters for Disease Control and Prevention (CDC), Atlanta, Georgia, USA.
Italo B ZeccaDepartment of Veterinary Integrative Biosciences, Texas A&M University, College Station, Texas, USA.
Ria R GhaiCenters for Disease Control and Prevention (CDC), Atlanta, Georgia, USA.
Casey Barton BehraveshCenters for Disease Control and Prevention (CDC), Atlanta, Georgia, USA.
Rebecca S B FischerSchool of Public Health, Texas A&M University, College Station, Texas, USA.
Gabriel L HamerDepartment of Entomology, Texas A&M University, College Station, Texas, USA.ORCID 0000-0002-9829-788X
Sarah A HamerDepartment of Veterinary Integrative Biosciences, Texas A&M University, College Station, Texas, USA.ORCID 0000-0002-4955-048X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Monitoring the zoonotic potential of emerging SARS-CoV-2 variants in animals is a critical tool to protect public health. We conducted a longitudinal study in 47 households reporting people with COVID-19 in Texas from January to July 2022, during the first Omicron wave. We evaluated 105 people and 100 of their companion animals for SARS-CoV-2 infection at three sequential sampling events, starting 0-5 days after the first reported diagnosis of COVID-19 in the house. SARS-CoV-2 RNA was detected in 68% of people from 43 households; 95.5% of people had antibodies to SARS-CoV-2. Dogs were the only animal species positive by RT-qPCR (5.4%; 3/55), and their viral loads were consistently lower compared with those from household members. Additionally, infected dogs did not yield infectious virus. Clusters of Omicron BA.1.1, BA.2.3.4, and BA.5.1.1 in people, dogs, and a dog food bowl confirmed human-to-dog transmission within households, with no evidence of onward transmission from the infected dogs. Eleven dogs (

Indexed as

COVID-19SARS-CoV-2AdolescentAdultAgedAnimalsAntibodies, ViralCatsChildChild, PreschoolDog DiseasesDogsFamily CharacteristicsFemaleHumansLongitudinal StudiesAntibodies, ViralRNA, ViralCOVID-19longitudinal studyOne Healthsurveillancezoonosis

Identifiers

PMID40600703
PMCPMC12306159

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.