Evidence map›Paper›PMID 40600545›Full record

ArticleCurrent medical imaging2025

Efficacy and Related Factors of Ultrasound-guided Lauromacrogol Injection in Treating Symptomatic Hepatic Cysts with a Diameter of <10 cm: A Retrospective Study

Qingyin Fu, Bin Hu, Jixian Lin, Qiping Liu, Tonghui Yang, Qiong Chen

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Article in Current medical imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Qingyin FuDepartment of Ultrasound, Minhang Hospital, Fudan University, Shanghai, China.ORCID 0009-0000-6048-4332
Bin HuDepartment of Ultrasound, Minhang Hospital, Fudan University, Shanghai, China.
Jixian LinDepartment of Neurology, Minhang Hospital, Fudan University, Shanghai, China.
Qiping LiuDepartment of Ultrasound, Minhang Hospital, Fudan University, Shanghai, China.
Tonghui YangDepartment of Ultrasound, Minhang Hospital, Fudan University, Shanghai, China.
Qiong ChenDepartment of Radiology, Dahua Hospital, Xuhui District, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsThis study aimed to retrospectively analyze the curative effect and influencing factors of lauromacrogol in the treatment of symptomatic hepatic cysts of <10 cm.

methodsIn this study, a total of 51 patients with symptomatic hepatic cysts (maximum diameter ranging from 5 cm to 10 cm) were included. Polycystic Liver Disease Questionnaire (PLD-Q) was used to evaluate the symptoms of patients prior to treatment. The patients were followed up at 1, 3, 6, and 12 months after treatment. At the 12-month follow-up, patients were asked to fill out the PLD-Q to assess their symptoms. The improvement rate of patients' symptoms was evaluated using a 5-point Likert scale (worse, 1; slight difference, 2; roughly the same, 3; good, and 4; better, 5. Volume reduction rate (VRR) was calculated by measuring the volume of the cyst cavity via ultrasound. Treatment success at the 12-month follow-up was determined using two criteria: symptom improvement and changes in cyst volume. Symptom improvement was assessed using a Likert Scale, with a score greater than 3 points indicating significant improvement. Additionally, a volume reduction rate (VRR) of 50% or more in cyst size (VRR ≥ 50%) was considered an effective treatment outcome. The relationship between the clinical factors and the ultrasonographic manifestations of hepatic cysts, including the initial maximum diameter of the cyst (measured using ultrasound before operation), the initial volume of the cyst, and the formation of septa after sclerosis of the cyst, was analyzed.

resultsAll patients completed at least 12 months of follow-up. After a 12-month follow-up, the effective and ineffective rates were 96.1% (49/51) and 3.9% (2/51), respectively. The logistic regression univariate analysis showed significant differences in the initial cyst volume (p = 0.001), the initial maximum diameter of the cyst (p = 0.005), and the interval formation after cyst sclerosis (p = <0.001) between VRR ≥ 50% and VRR < 50%. Logistic regression analysis demonstrated that septa formation after cyst sclerosis was an independent factor related to treatment failure, with an odds ratio of 3.246 (95% confidence interval, 0.784-4.148).

conclusionLauromacrogol is an effective method for hepatic cyst treatment. Septa formation after cyst sclerosis is an independent factor related to ineffective treatment.

Indexed as

CystsLiver DiseasesPolyethylene GlycolsSclerosing SolutionsUltrasonography, InterventionalAdultAgedFemaleHumansMaleMiddle AgedPolidocanolRetrospective StudiesTreatment OutcomePolidocanolPolyethylene GlycolsSclerosing SolutionsHepatic cystLauromacrogolLikert scaleLogistic regression analysis.SclerotherapyUltrasound-guided puncture

Identifiers

PMID40600545
PMCPMC12776549

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.