Evidence map›Paper›PMID 40600427›Full record

ArticleElectrophoresis2025

Capillary Electrophoresis Can Detect the Simultaneous Presence of Hairpins and Self-Dimers in Non-Symmetric, Single-Stranded DNA Oligomers.

Earle Stellwagen, Nancy C Stellwagen

Abstract read
In one paragraph

Article in Electrophoresis, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Earle StellwagenDepartment of Biochemistry, University of Iowa, Iowa City, Iowa, USA.
Nancy C StellwagenDepartment of Biochemistry, University of Iowa, Iowa City, Iowa, USA.ORCID 0000-0003-1146-8867

Funding

FREE SOLUTION MOBILITY AS A PROBE OF DNA ELECTROSTATICSR01GM061009 · NIGMS · UNIVERSITY OF IOWA · PI STELLWAGEN, NANCY C · 2001 to 2004
$958k
Analytical and Surface Chemistry Program of the National Science Foundation CHE0748271NIGMS NIH HHS GM061009NIGMS NIH HHS R01 GM061009
6 · The paper itself

Abstract

Free solution capillary electrophoresis (CE) has been used to show that non-symmetric, single-stranded DNA oligomers containing 26 nucleotides can exhibit peaks in the electropherograms that correspond to the simultaneous presence of self-dimers and hairpins in the solution. The overlapping hairpin and self-dimer peaks were observed at temperatures close to 15°C in background electrolytes containing at least 80 mM Na

Indexed as

DNA, Single-StrandedOligodeoxyribonucleotidesDimerizationElectrophoresis, CapillaryNucleic Acid ConformationTemperatureDNA, Single-StrandedOligodeoxyribonucleotidescapillary electrophoresisDNA hairpinsself‐dimerssingle‐stranded DNA oligomers

Identifiers

PMID40600427
PMCPMC12366245

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.