ArticleJournal of cosmetic dermatology2025
Histologic Study of Abdominal Skin Treated With Mechanical Dermal Micro-Coring Technology for Minimally Invasive Skin Removal.
Article in Journal of cosmetic dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Histologic Study of Abdominal Skin Treated With Mechanical Dermal Micro-Coring Technology for Minimally Invasive Skin Removal.Journal of cosmetic dermatology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
backgroundMechanical Dermal Micro-Coring Technology (MCT; Ellacor System) achieves skin tightening and wrinkle reduction through direct mechanical excision of skin cores using hollow needles and collagen stimulation via the wound-healing response.
aimsTo evaluate histopathology and immunohistochemistry of the skin and subcutaneous tissue after a single and multiple treatments with MCT. PATIENTS/
methodsIn this single-center pilot study, 6 female patients scheduled to undergo abdominoplasty were divided into 2 cohorts. Subjects in cohort 1 (safety cohort) received 1 MCT treatment at a depth of 4 mm, 5 mm, and 7 mm, each administered at 1 of 3 unique test areas, with tissue sampling/abdominoplasty 30 days after treatment. Subjects in cohort 2 received 1, 2, or 3 4 mm-depth treatments at 1 of 3 unique test sites, with 30-day intervals for > 1 treatment. Tissue sampling/abdominoplasty occurred 90 days after initial treatment. Histopathology was performed at a central laboratory, and biopsies were evaluated using H&E, Herovici, and Movat stains by blinded evaluators.
resultsA robust increase in new collagen compared to the control tissue was observed for 1 to 3 treatments in all samples. There was no evidence of inflammation or scarring, consistent with earlier preclinical and clinical histology.
conclusionsMCT-associated histological changes confirm that in addition to skin removal, treatment results in an increase in collagen and homogenization of the dermis in the treated area.
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Registered trials
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