Evidence map›Paper›PMID 40600330›Full record

ArticleFuture medicinal chemistry2025

New and potential boron-containing compounds for treatment of Alzheimer's disease and cancers.

Ferah Comert Onder, Kadircan Ural, Alper Onder, Bulent Ozpolat, Mehmet Ay

Abstract read
In one paragraph

Article in Future medicinal chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Design, Synthesis,ACS omega · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ferah Comert OnderDepartment of Medical Biology, Faculty of Medicine, Çanakkale Onsekiz Mart University, Çanakkale, Türkiye.ORCID 0000-0002-4037-1979
Kadircan UralDepartment of Medical System Biology, School of Graduate Studies, Çanakkale Onsekiz Mart University, Çanakkale, Türkiye.ORCID 0009-0002-1287-1308
Alper OnderDepartment of Chemistry, Natural Products and Drug Research Laboratory, Faculty of Science, Çanakkale Onsekiz Mart University, Çanakkale, Türkiye.ORCID 0000-0002-0775-0053
Bulent OzpolatDepartment of Nanomedicine, Houston Methodist Research Institute, Houston, TX USA.ORCID 0000-0001-8602-7463
Mehmet AyDepartment of Chemistry, Natural Products and Drug Research Laboratory, Faculty of Science, Çanakkale Onsekiz Mart University, Çanakkale, Türkiye.ORCID 0000-0002-1095-1614

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimIn this study, new boron-containing carbamate compounds were synthesized and evaluated as potential acetylcholinesterase (AChE) inhibitors by in vitro and in silico analyses. MATERIALS &

methodsThe structures were characterized by spectroscopic analysis including

resultsBased on our findings, compounds (

conclusionOur study indicates the discovery of new boron-containing AChE inhibitors as potential candidates for the treatment of Alzheimer's disease and cancer.

Indexed as

Alzheimer DiseaseAntineoplastic AgentsBoron CompoundsCarbamatesCholinesterase InhibitorsNeoplasmsHT29 CellsHumansInhibitory Concentration 50MCF-7 CellsMolecular Docking SimulationStructure-Activity RelationshipTacrineAntineoplastic AgentsBoron CompoundsCarbamatesCholinesterase InhibitorsTacrineAChEAlzheimer’s diseaseanticancerBoronMD simulation

Identifiers

PMID40600330
PMCPMC12296104

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.