Evidence map›Paper›PMID 40600310›Full record

ArticleJournal of medical entomology2025

Larvicidal activity of Trichoderma atroviride (Hypocreales: Hypocreaceae) against Aedes albopictus (Diptera: Culicidae).

David T Hayes, Patil Tawidian, Ethan Schubert, Qing Kang, Amare J Sumpter, Kristin Michel

Abstract read
In one paragraph

Article in Journal of medical entomology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

David T HayesDivision of Biology, Kansas State University, Manhattan, KS, USA.
Patil TawidianDivision of Biology, Kansas State University, Manhattan, KS, USA.
Ethan SchubertDepartment of Statistics, Kansas State University, Manhattan, KS, USA.
Qing KangDepartment of Statistics, Kansas State University, Manhattan, KS, USA.
Amare J SumpterDivision of Biology, Kansas State University, Manhattan, KS, USA.
Kristin MichelDivision of Biology, Kansas State University, Manhattan, KS, USA.ORCID 0000-0001-9769-5248

Funding

The protease network that regulates innate immunity in mosquitoesR01AI140760 · NIAID · KANSAS STATE UNIVERSITY · PI MICHEL, KRISTIN · 2018 to 2022
$2.8M
National Institute of Allergy and Infectious DiseasesNational Institute of Food and AgricultureNIAID NIH HHS R01 AI140760NIH HHS
6 · The paper itself

Abstract

Larviciding is an important part of effective integrated mosquito management. However, growing resistance to chemical- and bacterial-based insecticides requires biocontrol agents with novel modes of action. Entomopathogenic fungi are good candidates for larval control due to their capability to infect mosquito larvae and their production of larvicidal compounds. In this study, we isolated a strain of Trichoderma atroviride from Aedes albopictus larvae collected in Manhattan, KS, USA. We used a laboratory-based microcosm assay to expose L3 Ae. albopictus larvae to T. atroviride conidia and culture supernatant treatments. Larvae were monitored daily for survival and development to pupae and adults. In addition, adult survival was monitored for 10 d postpupation, and wing lengths were measured to assess mosquito size. Our results revealed that T. atroviride culture supernatant was a potent larvicide toward Ae. albopictus. However, conidia by themselves were not larvicidal, indicating the major mode of killing was through toxicity exerted by the culture supernatant. We further show that larval exposure to T. atroviride supernatant delayed larval development to pupae. Sex-specific adult survival was not affected by larval exposure to T. atroviride. However, wing length of male and female mosquitoes were reduced, indicating a reduction in adult mosquito body size as compared to the control. Taken together, this study identifies the culture supernatant from a novel strain of T. atroviride as a potent larvicide of Ae. albopictus, potentially expanding the toolbox for biological control of mosquitoes.

Indexed as

AedesMosquito ControlPest Control, BiologicalTrichodermaAnimalsFemaleLarvaMalePupaSpores, FungalbiocontrolentomotoxinFunguslarvicidemosquito control

Identifiers

PMID40600310
PMCPMC12570157

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.