Evidence map›Paper›PMID 40600229›Full record

ArticleCancer diagnosis & prognosis

Characteristics and Outcomes of Patients Who Underwent Curative Resection for Colorectal Cancer Local Recurrence.

Keizaburo Maruyama, Tetsuro Tominaga, Takashi Nonaka, Yuma Takamura, Hiroki Katayama, Shintaro Hashimoto, Mariko Yamashita, Keisuke Noda, Rika Ono, Mitsutoshi Ishii and 4 more

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Article in Cancer diagnosis & prognosis. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Keizaburo MaruyamaDepartment of Surgery, Sasebo Chuo Hospital, Sasebo, Japan.
Tetsuro TominagaDepartment of Surgical Oncology, Nagasaki University Graduate School of Biomedical Science, Nagasaki, Japan.
Takashi NonakaDepartment of Surgical Oncology, Nagasaki University Graduate School of Biomedical Science, Nagasaki, Japan.
Yuma TakamuraDepartment of Surgical Oncology, Nagasaki University Graduate School of Biomedical Science, Nagasaki, Japan.
Hiroki KatayamaDepartment of Surgical Oncology, Nagasaki University Graduate School of Biomedical Science, Nagasaki, Japan.
Shintaro HashimotoDepartment of Surgical Oncology, Nagasaki University Graduate School of Biomedical Science, Nagasaki, Japan.
Mariko YamashitaDepartment of Surgical Oncology, Nagasaki University Graduate School of Biomedical Science, Nagasaki, Japan.
Keisuke NodaDepartment of Surgical Oncology, Nagasaki University Graduate School of Biomedical Science, Nagasaki, Japan.
Rika OnoDepartment of Surgery, Sasebo City General Hospital, Sasebo, Japan.
Mitsutoshi IshiiDepartment of Surgery, Sasebo City General Hospital, Sasebo, Japan.
Makoto HisanagaDepartment of Surgery, Sasebo City General Hospital, Sasebo, Japan.
Kaido OishiDepartment of Surgery, National Hospital Organization Nagasaki Medical Center, Nagasaki, Japan.
Fumitake UchidaDepartment of Surgery, Ureshino Medical Center, Ureshino, Japan.
Keitaro MatsumotoDepartment of Surgery, Sasebo Chuo Hospital, Sasebo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background/Aim: The standard treatment for local recurrence (LR) is radical resection where possible, and R0 resection is reportedly associated with improved prognosis. However, the surgery for LR is complex and difficult, resulting in a low resection rate of 13-23%. The aim of this study was to examine clinical characteristics of LR and survival outcome after R0 resection of LR. Patients and Methods: We retrospectively reviewed the medical records of 18 patients who underwent curative surgery for colorectal cancer LR at four hospitals between April 2016 and March 2024. We examined the perioperative outcomes and prognosis of LR treated with R0 resection. Results: Pathological T4 was seen in 9 of 18 patients (50.0%), N-positive status in 12 (66.7%), and lymphovascular invasion in 15 (83.3%). Median interval from primary surgery to local recurrence was 24 months. Postoperative complications occurred in 9 patients (50.0%). Eight patients (44.4%) experienced re-recurrence, with peritoneal metastasis in 5 patients, liver metastasis in one, lung metastasis in one, and adrenal gland metastasis in one. Five-year RFS was 39.4% and 5-year OS was 52.2%. Conclusion: Postoperative LR of colorectal cancer is expected to show relatively favorable prognosis with R0 resection. LR often occurs within 3 years, and careful follow-up is necessary for high-risk cases.

Indexed as

Colorectal cancerlocal recurrenceoverall survivalR0 resectionrecurrence-free survival

Identifiers

PMID40600229
PMCPMC12208202

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