ArticleCancer diagnosis & prognosis
Investigation of the Biological Properties of Non-small Cell Lung Cancer Using Three-dimensional Computed Tomography Images.
Article in Cancer diagnosis & prognosis. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 authors.
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Abstract
Background/Aim: We investigated the biological properties of non-small cell lung cancer (NSCLC) using three-dimensional computed tomography (3D-CT) images. Patients and Methods: We measured the diameters of surgically resected NSCLCs in the direction to the hilum and in the direction orthogonal to the hilum on the two largest cross-sections using 3D images, and classified NSCLCs into three types according to their shape. Correlations between each type and clinicopathological factors were determined. Results: We examined 369 cases: 129 Type A, 182 Type B, and 58 Type C. The tumor-shape types demonstrated significant correlations with histological type, tumor size, and pathological tumor size (pT), lymphatic invasion (Ly), and pleural invasion (pl) factors. There were significant correlations between Type A and adenocarcinoma (Ad), and between Type C and advanced T factor or larger size. The frequency of lymphatic invasion was increased in Type A but decreased in Type C, whereas pleural invasion was increased in Type C. Conclusion: NSCLC tumor shapes showed biological properties according to each histological type, such as pleural invasion or lymphatic invasion.
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