Evidence map›Paper›PMID 40600216›Full record

ArticleAmerican journal of ophthalmology case reports2025

Ocular manifestations of reactive infectious mucocutaneous eruption (RIME) secondary to adenovirus: A case report.

L H Young, S B Kim, J S Takhar, L D Sun, K M White, A F Omar

Abstract readCase Reports
In one paragraph

Article in American journal of ophthalmology case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

L H YoungCase Western Reserve University School of Medicine. Cleveland, OH, USA.
S B KimCase Western Reserve University School of Medicine. Cleveland, OH, USA.
J S TakharCase Western Reserve University School of Medicine. Cleveland, OH, USA.
L D SunCase Western Reserve University School of Medicine. Cleveland, OH, USA.
K M WhiteCase Western Reserve University School of Medicine. Cleveland, OH, USA.
A F OmarCase Western Reserve University School of Medicine. Cleveland, OH, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To present an atypical case of reactive infectious mucocutaneous eruption (RIME) in an adult patient attributed to primary adenoviral infection. Observations: This is a case describing the clinical course of a previously healthy 34-year old man who presented with acute onset urethritis and bilateral conjunctivitis. His left eye conjunctivitis progressed to pseudomembrane and symblepharon formation within days. His clinical course was marked by progressive worsening of urethritis and formation of mucus membrane ulceration and bullae even after antibiotic treatment and aggressive topical lubrication. He required admission and a multidisciplinary team made the diagnosis of adenovirus-induced RIME. He was treated with intravenous steroids and intravenous cyclosporine. He ultimately recovered with a good visual outcome. Conclusions and importance: This case demonstrates a rare case of RIME in an adult triggered by an adenovirus infection. Multidisciplinary care is key to diagnosis and treatment.

Indexed as

AdenovirusConjunctivitisReactive infectious mucocutaneous eruption (RIME)

Identifiers

PMID40600216
PMCPMC12209892

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.