Evidence map›Paper›PMID 40600120›Full record

ArticleRadiology case reports2025

Malignant peripheral nerve sheath tumor of the shoulder: A rare case highlighting the role of multimodal management.

Oukassem Siham, Abourak Chaimae, Sqalli Houssaini Abdelkader, Guennouni Asma, Moatassim Billah Nabil, Ittimad Nassar, Imrani Kaoutar, Iraqui Iman, Derqaoui Sabrine, Znati Kaoutar

Abstract readCase Reports
In one paragraph

Article in Radiology case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Oukassem SihamRadiology Central Department, Ibn Sina University Hospital, Mohammed V University, Rabat, Morocco.
Abourak ChaimaeRadiology Central Department, Ibn Sina University Hospital, Mohammed V University, Rabat, Morocco.
Sqalli Houssaini AbdelkaderRadiology Central Department, Ibn Sina University Hospital, Mohammed V University, Rabat, Morocco.
Guennouni AsmaRadiology Central Department, Ibn Sina University Hospital, Mohammed V University, Rabat, Morocco.
Moatassim Billah NabilRadiology Central Department, Ibn Sina University Hospital, Mohammed V University, Rabat, Morocco.
Ittimad NassarRadiology Central Department, Ibn Sina University Hospital, Mohammed V University, Rabat, Morocco.
Imrani KaoutarRadiology Central Department, Ibn Sina University Hospital, Mohammed V University, Rabat, Morocco.
Iraqui ImanDepartment of Pathology, Ibn Sina University Hospital Center. Mohammed V University, Rabat, Morocco.
Derqaoui SabrineDepartment of Pathology, Ibn Sina University Hospital Center. Mohammed V University, Rabat, Morocco.
Znati KaoutarDepartment of Pathology, Ibn Sina University Hospital Center. Mohammed V University, Rabat, Morocco.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Malignant peripheral nerve sheath tumors (MPNSTs) are rare and aggressive sarcomas often associated with neurofibromatosis type 1 (NF1) or prior radiation therapy. We report the case of a 26-year-old male who presented with a rapidly enlarging, painful mass in the left shoulder initially misdiagnosed as an abscess. MRI revealed a large extra-compartmental lesion with heterogeneous enhancement infiltrating the trapezius muscle. Histopathology confirmed MPNST, showing high mitotic activity (16/10 HPF), 10% necrosis, and a Ki-67 index of 40%, with diffuse Sox10 and focal S100 positivity. The patient received neoadjuvant radiotherapy followed by complete surgical excision and defect reconstruction using a pedicled trapezius flap and a split-thickness skin graft. This case highlights the importance of early imaging, multidisciplinary planning, and multimodal treatment in the management of MPNSTs.

Indexed as

MPNSTMRISoft tissue sarcomaSurgical resection

Identifiers

PMID40600120
PMCPMC12209943

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.