ArticleCureus2025
Slowing Myopia Progression in Adolescents Using Orthokeratology: A Retrospective Chart Review.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
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Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThis study evaluated the effectiveness of orthokeratology (ortho-k) in reducing myopia progression rates in adolescents from a rural Appalachian community by comparing pre- and post-treatment clinical measures of refractive error and corneal curvature.
methodsA retrospective chart review was conducted on 45 adolescents (90 eyes, aged 8-16) who had been treated with ortho-k for at least six months at a rural optometry practice. Post-treatment clinical data were obtained between 21 and 90 days of treatment discontinuation. Refractive error, corneal curvature (k values), and adverse events were collected and statistically analyzed, with myopia progression rates compared to the published untreated rate of -0.50 diopters per year (D/y).
resultsThe mean myopia progression rate was -0.227 ± 0.351 D/y, significantly slower than the untreated rate (p < 0.001). A subgroup with corneal flattening (n = 11 eyes) showed a progression rate of -0.028 ± 0.134 D/y. Post-treatment corneal curvature steepened on average (Δkm = 0.327 ± 0.445 D), but flattening was linked to slower progression. No significant effects of sex, age, or treatment duration were found in the full sample, although male patients in the flattened subgroup had slower progression than female patients (p = 0.014). No adverse events were reported.
conclusionOrtho-k significantly reduces myopia progression in adolescents, particularly in those with corneal flattening, as demonstrated by a slower progression rate compared to untreated individuals. Its safety and effectiveness make it a valuable treatment option for managing myopia in rural communities.
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