Evidence map›Paper›PMID 40600077›Full record

ArticleCureus2025

Risk Factors Associated With Unplanned Conversion to Open in Radical and Partial Nephrectomy.

Benjamin A Fink, Young Son, Kimberly C Toumazos, Virgil K DeMario, Joseph P Flemming, Nikki Covelle, Logan B Wesemann, Edward Wu, Vaishnavi J Patel, Devki Patel and 1 more

Abstract read
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Benjamin A FinkDepartment of Urology, Jefferson Health, Stratford, USA.
Young SonDepartment of Urology, Jefferson Stratford Hospital, Stratford, USA.
Kimberly C ToumazosDepartment of Urology, University of Kentucky College of Medicine, Lexington, USA.
Virgil K DeMarioDepartment of Clinical and Applied Science Education, University of the Incarnate Word School of Osteopathic Medicine, San Antonio, USA.
Joseph P FlemmingDepartment of Medicine, Rowan-Virtua School of Osteopathic Medicine, Stratford, USA.
Nikki CovelleDepartment of Urology, Jefferson Health, Stratford, USA.
Logan B WesemannDepartment of Urology, Rocky Vista University College of Osteopathic Medicine, Ivins, USA.
Edward WuDepartment of Urology, Maimonides Medical Center, Brooklyn, USA.
Vaishnavi J PatelOffice of Research and Innovation, University of the Incarnate Word School of Osteopathic Medicine, San Antonio, USA.
Devki PatelOffice of Research and Innovation, Texas Tech University Health Sciences Center Paul L. Foster School of Medicine, Lubbock, USA.
Thomas J MuellerDepartment of Urology, Jefferson Health, Stratford, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction Minimally invasive surgery (MIS), such as laparoscopic and robotic techniques, has become standard in kidney surgery due to its benefits in offering faster recovery while maintaining comparable oncologic outcomes when compared to open surgery. However, some cases still require unexpected conversion to open surgery, which can increase the risk of postoperative complications and increase the 30-day readmission risk. Predictors and risk factors for these conversions remain underexplored. This study uses the American College of Surgeons National Surgical Quality Improvement Program (ACS NSQIP) database to identify predictors and outcomes in nephrectomy patients, therefore improving patient selection for open surgeries. Methods Using the 2019-2020 NSQIP data, this retrospective study analyzed 14,186 patients, 4,862 of whom met the inclusion criteria of nephrectomy for kidney cancer. Patients were subcategorized into planned MIS (n=4,756) and unplanned conversion to open (UCO) (n=106). The Wilcoxon signed-rank test was utilized for continuous variables, and Fisher's exact test was performed for categorical variables, including chi-squared analysis. Statistical significance was set at a P-value of <0.05. Results Unplanned conversion to open rate was 2.2%. There was an increased incidence of unplanned conversion to open in T3 and T4 tumors (30.2% and 8.5%) compared to the planned group (21.2% and 0.50%). Patients in the American Society of Anesthesiologists (ASA) classification 3 and 4 categories were more likely to be within the unplanned group. Outcomes (readmission, blood transfusion, mean operative time, the length of stay, prolonged nil per os/nasogastric tube {NPO/NGT}, and lymphocele/lymphatic leak) were compared between the groups. Conclusion Higher tumor stage, higher ASA classification, deranged kidney function, and raised prothrombin time/international normalized ratio (PT/INR) were predictive factors for unplanned conversions, with worse outcomes such as prolonged hospitalizations and postoperative complications.

Indexed as

minimally invasive surgerypartial nephrectomyradical nephrectomyrenal cell carcinomaunplanned conversion to open

Identifiers

PMID40600077
PMCPMC12209969

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.