Evidence map›Paper›PMID 40600022›Full record

ArticleInnovation in aging2025

The Role of Social Support for Depressive Symptoms in Dementia: A Four-Year Longitudinal Study.

Iris Blotenberg, Lina Jeran, Francisca S Rodriguez, Bernhard Michalowsky, Moritz Platen, Stefan Teipel, Wolfgang Hoffmann, Jochen René Thyrian

Abstract read
In one paragraph

Article in Innovation in aging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Iris BlotenbergGerman Center for Neurodegenerative Diseases (DZNE), Greifswald, Germany.ORCID https://orcid.org/0000-0002-2273-5564
Lina JeranGerman Center for Neurodegenerative Diseases (DZNE), Greifswald, Germany.
Francisca S RodriguezGerman Center for Neurodegenerative Diseases (DZNE), Greifswald, Germany.ORCID https://orcid.org/0000-0003-2919-5510
Bernhard MichalowskyGerman Center for Neurodegenerative Diseases (DZNE), Greifswald, Germany.ORCID https://orcid.org/0000-0002-3425-0089
Moritz PlatenGerman Center for Neurodegenerative Diseases (DZNE), Greifswald, Germany.
Stefan TeipelGerman Center for Neurodegenerative Diseases (DZNE), Rostock, Germany.
Wolfgang HoffmannGerman Center for Neurodegenerative Diseases (DZNE), Greifswald, Germany.
Jochen René ThyrianGerman Center for Neurodegenerative Diseases (DZNE), Greifswald, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Objectives: Depressive symptoms are common in people with dementia, significantly reducing well-being and potentially exacerbating dementia symptoms. The objective of the present study was to investigate the role of support from the social environment for depressive symptoms in people with dementia over a 4-year period. Research Design and Methods: We used data from a cohort of 334 community-dwelling people with dementia ( Results: At the beginning of the study, 13.8% of people with dementia reported mild to severe depressive symptoms. People with more social support showed fewer depressive symptoms overall over the 4-year period (% change per point on a scale from 22 to 110: -1.2, 95% CI: -1.8, -0.4). In addition, a decline in a person's social support was associated with more depressive symptoms (% change: -0.9, 95% CI: -1.7, -0.2). These effects were stable even after controlling for sociodemographic (age, sex, education) and clinical factors (cognitive and functional status, comorbidities). Discussion and Implications: The social environment plays an important role in depressive symptoms in people with dementia-beyond clinical factors like cognitive and functional abilities. Improving support from the social environment could be a lever for alleviating depressive symptoms. In the care of people with dementia, not only medical needs but also psychosocial needs should come to the forefront.

Indexed as

Alzheimer’s diseaseMental healthNeurodegenerative diseasesNeuropsychiatric symptomsSocial health

Identifiers

PMID40600022
PMCPMC12210947

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.