Evidence map›Paper›PMID 40599911›Full record

ArticleBioinformation2025

Characterization of clear cell - Renal cell carcinoma using neutrophil - Lymphocyte ratio.

Santhosh S, Poulose Chally, Abdul Azeez, Shrikant Patel, Arifa Bakerywala, Heena Shaikh

Abstract read
In one paragraph

Article in Bioinformation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Santhosh SDepartment of Urology, Manipal Hospital Malleshwaram, Bengaluru, Karnataka, India.
Poulose ChallyDepartment of Urology, Consultant, Baby Memorial Hospital, Calicut Kerala, India.
Abdul AzeezDepartment of Urology, Consultant, Baby Memorial Hospital, Calicut Kerala, India.
Shrikant PatelPrivate practitioner, Shree ram dental clinic and implant centre, Bhavnagar, Gujarat, India.
Arifa BakerywalaDepartment of Pediatric dentistry, Tufts University School of Dental Medicine, United States of America.
Heena ShaikhDepartment of Healthcare Leadership, Trinity Western University, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The features of tumour in clear cell - renal cell carcinoma are evaluated using neutrophil - lymphocyte ratio for its prognosis. Hence, 186 clear cell-renal cell carcinoma patients with documented neutrophil lymphocyte ratio were obtained. Depending on the features of the lesion, patients underwent either a partial or radical nephrectomy and characteristics were studied in relation to normal or high neutrophil - lymphocyte ratio with a cut-off of 2.7. Of the 186 patients studied, 131 had a normal neutrophil lymphocyte ratio (<2.7), while 55 presented with an elevated neutrophil lymphocyte ratio (≥2.7). Elevated neutrophil lymphocyte ratio was significantly associated with both tumor size and renal vein invasion, with a p-value of less than 0.001. Thus, the neutrophil lymphocyte ratio is a valuable metric for assessing renal vein extension and predicting tumour size.

Indexed as

Clear cell carcinomaneutrophil-lymphocyte ratiorenal cell carcinomasurvival

Identifiers

PMID40599911
PMCPMC12208224

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.