Evidence map›Paper›PMID 40599827›Full record

ArticlePNAS nexus2025

Standoff detection of fentanyl hydrochloride via nuclear quadrupole resonance: A multimodality pursuit.

Michael W Malone, Harris E Mason, Adam R Altenhof, Michelle A Espy, Marc A Alvarez, Rami J Batrice, Amber J Day, Adam P Dioguardi, Michihiro Hirata, Margaret R Jones and 9 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PNAS nexus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Michael W MaloneMaterials Physics & Applications - Quantum, MPA-Q, Los Alamos National Laboratory, Los Alamos, NM 87545, USA.ORCID https://orcid.org/0000-0002-9721-1538
Harris E MasonInorganic, Isotope, and Actinide Chemistry, C-IIAC, Los Alamos National Laboratory, Los Alamos, NM 87545, USA.ORCID https://orcid.org/0000-0002-1840-0550
Adam R AltenhofMaterials Physics & Applications - Quantum, MPA-Q, Los Alamos National Laboratory, Los Alamos, NM 87545, USA.ORCID https://orcid.org/0000-0002-8095-6373
Michelle A EspyNondestructive Testing & Evaluation, V-6, Los Alamos National Laboratory, Los Alamos, NM 87545, USA.ORCID https://orcid.org/0000-0001-8427-3513
Marc A AlvarezBiochemistry and Biotechnology, BTEK, Los Alamos National Laboratory, Los Alamos, NM 87545, USA.
Rami J BatriceBiochemistry and Biotechnology, BTEK, Los Alamos National Laboratory, Los Alamos, NM 87545, USA.ORCID https://orcid.org/0000-0001-5368-3106
Amber J DayDepartment of Statistics and Data Sciences, The University of Texas at Austin, Austin, TX 78712, USA.
Adam P DioguardiMaterials Physics & Applications - Quantum, MPA-Q, Los Alamos National Laboratory, Los Alamos, NM 87545, USA.ORCID https://orcid.org/0000-0001-6562-8032
Michihiro HirataMaterials Physics & Applications - Quantum, MPA-Q, Los Alamos National Laboratory, Los Alamos, NM 87545, USA.ORCID https://orcid.org/0000-0003-2027-751X
Margaret R JonesInorganic, Isotope, and Actinide Chemistry, C-IIAC, Los Alamos National Laboratory, Los Alamos, NM 87545, USA.
Natalie E KleinStatistical Sciences, CCS-6, Los Alamos National Laboratory, Los Alamos, NM 87545, USA.ORCID https://orcid.org/0000-0002-7532-4013
Ann E MattssonComputational Physics Division, XCP-5, Los Alamos National Laboratory, Los Alamos, NM 87545, USA.ORCID https://orcid.org/0000-0002-0677-7537
Shaun G NewmanMaterials Physics & Applications - Quantum, MPA-Q, Los Alamos National Laboratory, Los Alamos, NM 87545, USA.
Daniel A RehnComputational Physics Division, XCP-5, Los Alamos National Laboratory, Los Alamos, NM 87545, USA.ORCID https://orcid.org/0000-0001-5139-0393
Aaron M TondreauInorganic, Isotope, and Actinide Chemistry, C-IIAC, Los Alamos National Laboratory, Los Alamos, NM 87545, USA.ORCID https://orcid.org/0000-0003-0440-5497
Kamal WagleComputational Physics Division, XCP-5, Los Alamos National Laboratory, Los Alamos, NM 87545, USA.
Robert F WilliamsBiochemistry and Biotechnology, BTEK, Los Alamos National Laboratory, Los Alamos, NM 87545, USA.ORCID https://orcid.org/0000-0002-4310-6249
Ruilian WuBiochemistry and Biotechnology, BTEK, Los Alamos National Laboratory, Los Alamos, NM 87545, USA.
Michael T JanickeNuclear and Radiation Studies Board, National Academy of Sciences, Washington, DC 20001, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Synthetic opioids, chiefly fentanyl, are responsible for nearly 70% of global annual drug deaths due to their extreme toxicity, ease of manufacture, and addictiveness. We show the magnetic resonance technique of nuclear quadrupole resonance (NQR) spectroscopy can be used for the standoff detection of fentanyl hydrochloride (HCl), likely the most common illicit synthetic opioid, even through opaque packaging such as cardboard, plastic, and glass. Combining work in synthesis, crystallography, density functional theory, and nuclear magnetic resonance, we report the electric field gradient tensor parameters of the

Indexed as

detectionfentanylNQRsynthetic opioids

Identifiers

PMID40599827
PMCPMC12210233

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.