Evidence map›Paper›PMID 40599708›Full record

ArticleAesthetic surgery journal. Open forum2025

Myospasm and Fasciculation After Botulinum Toxin Injection.

Xueqing Li, Zhaowei Zhu, Min Zhu, Yanting Zheng

Abstract readCase Reports
In one paragraph

Article in Aesthetic surgery journal. Open forum, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Zhaowei Zhu
Min Zhu
Yanting Zheng

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Botulinum toxin type A (BTA) is commonly used to treat dystonia; however, reports of dystonia caused by BTA are rare. In this case study, the authors aimed to illustrate the instances of dystonia after cosmetic injections of BTA. Three cases were retrospectively analyzed, with follow-up evaluations conducted to assess the development and resolution of symptoms. Injection techniques, including microdroplet and intradermal methods, were examined, and potential hypotheses regarding the etiology of dystonia were explored. Recommendations for mitigating adverse effects were formulated based on the analysis of injection practices, including modifications to dosage, injection-site distribution, and volume. In all cases, patients experienced transient dystonia following BTA injections, with symptoms including muscle spasms and abnormal muscle contractions, which resolved spontaneously or with minor interventions. The findings suggest that the use of microdroplet techniques and careful injection strategies can minimize the risk of such adverse effects. In conclusion, the authors suggest that neurological injury, neuromuscular junction impact, uneven drug distribution, and imbalance between denervation and functional recovery may cause dystonia. Level of Evidence 5 Diagnostic:

Identifiers

PMID40599708
PMCPMC12209808

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.