Evidence map›Paper›PMID 40599632›Full record

ArticleCase reports in psychiatry2025

Unexpected Adverse Effect of Haloperidol: Acute Tongue Angioedema in a Schizophrenic Patient-Case Report and Review.

Nadia Romdhane, Dorra Chiboub, Ameni Amri, Asma Ayedi, Emna Rejeb, Imen Zoghlami, Safa Nefzaoui, Ines Hariga, Chiraz Mbarek

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Case reports in psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Nadia RomdhaneEars Nose and Throat, Head and Neck Surgery Department, Habib Thameur Hospital, Tunis, Tunisia.
Dorra ChiboubEars Nose and Throat, Head and Neck Surgery Department, Habib Thameur Hospital, Tunis, Tunisia.
Ameni AmriEars Nose and Throat, Head and Neck Surgery Department, Habib Thameur Hospital, Tunis, Tunisia.ORCID https://orcid.org/0009-0009-7290-6278
Asma AyediEars Nose and Throat, Head and Neck Surgery Department, Habib Thameur Hospital, Tunis, Tunisia.
Emna RejebEars Nose and Throat, Head and Neck Surgery Department, Habib Thameur Hospital, Tunis, Tunisia.
Imen ZoghlamiEars Nose and Throat, Head and Neck Surgery Department, Habib Thameur Hospital, Tunis, Tunisia.
Safa NefzaouiEars Nose and Throat, Head and Neck Surgery Department, Habib Thameur Hospital, Tunis, Tunisia.
Ines HarigaEars Nose and Throat, Head and Neck Surgery Department, Habib Thameur Hospital, Tunis, Tunisia.
Chiraz MbarekEars Nose and Throat, Head and Neck Surgery Department, Habib Thameur Hospital, Tunis, Tunisia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Angioedema of the tongue, also known as angioneurotic, or Quinke edema is a swelling of the tongue due to plasma leaking from capillary and postcapillary venules into deep submucosal tissue. This condition can either be hereditary, or acquired, due to allergy induced reactions for example. With an acute onset, this phenomenon can potentially be life threatening due to sudden and complete upper airway obstruction. Our aim is to describe the case of a 54-year-old schizophrenic male patient who presented with an angioedema of the tongue occurring after oral administration of haloperidol, a first-generation antipsychotic. The patient was admitted for close respiratory monitoring. The established cause for this condition was an allergic reaction to haloperidol. The following course was a favorable outcome with complete resolution of the edema without respiratory distress. We aim to report our case and to delve into other existing similar cases reported thus far in literature.

Indexed as

airway obstructionantipsychotic agentsdrugsedema

Identifiers

PMID40599632
PMCPMC12213041

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