Evidence map›Paper›PMID 40599628›Full record

ArticleClinical kidney journal2025

Renal denervation in dialysis patients: long-term outcomes in a real-world setting.

Concetta Gangemi, Alessia Gambaro, Vittorio Ortalda, Domenico Tavella, Chiara Caletti, Simone Fezzi, Beatrice Bianco, Elisa De Tomi, Giovanni Gambaro, Flavio Luciano Ribichini and 1 more

Abstract read
In one paragraph

Article in Clinical kidney journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Guideline
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Concetta GangemiDivision of Nephrology, Department of Medicine, University of Verona, Verona, Italy.
Alessia GambaroDivision of Cardiology, Department of Medicine, University of Verona, Verona, Italy.ORCID https://orcid.org/0000-0001-8341-1427
Vittorio OrtaldaDivision of Nephrology, Department of Medicine, University of Verona, Verona, Italy.
Domenico TavellaDivision of Cardiology, Department of Medicine, University of Verona, Verona, Italy.
Chiara CalettiDivision of Nephrology, Department of Medicine, University of Verona, Verona, Italy.
Simone FezziDivision of Cardiology, Department of Medicine, University of Verona, Verona, Italy.
Beatrice BiancoDivision of Nephrology, Department of Medicine, University of Verona, Verona, Italy.
Elisa De TomiDivision of Nephrology, Department of Medicine, University of Verona, Verona, Italy.ORCID https://orcid.org/0000-0002-1368-374X
Giovanni GambaroDivision of Nephrology, Department of Medicine, University of Verona, Verona, Italy.ORCID https://orcid.org/0000-0001-5733-2370
Flavio Luciano RibichiniDivision of Cardiology, Department of Medicine, University of Verona, Verona, Italy.
GITIAR team

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Resistant hypertension is common in patients with end-stage kidney disease (ESKD) who are on dialysis. Experience with percutaneous renal denervation (RDN) in these patients is limited and generally has short follow-up periods, primarily focusing on blood pressure (BP) control. In particular, the effects of RDN on anaemia, chronic kidney disease-mineral and bone disorder (CKD-MBD) and dialysis tolerance remain unexamined. Methods: We report our experience with RDN in 14 dialysis patients [7 on haemodialysis (HD) and 7 on peritoneal dialysis (PD)] with a follow-up after RDN of 3-84 months. Six patients received kidney transplantation during follow-up. Results: BP and the number of antihypertensive drugs decreased ( Conclusion: Our experience with RDN in dialysis patients suggests beneficial effects in both HD and PD. BP improved significantly, with no observed issues related to the typical clinical problems faced by these patients, such as anaemia, CKD-MBD and dialysis tolerance. Furthermore, in those patients who received a kidney transplant, we noted a further improvement in BP control.

Indexed as

dialysisrenal denervationresistant hypertensiontransplantationuraemia complications

Identifiers

PMID40599628
PMCPMC12209812

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.