Evidence map›Paper›PMID 40599561›Full record

ArticleGastro hep advances2025

Internal Fistulas Discovered on Cross-Sectional Imaging Predict Future Intra-Abdominal Abscesses.

Vikas J Patel, Maher Homsi, Nicholas A Orriols, Naueen A Chaudhry, Joseph R Grajo, Abdullah Malkawi, Patricia Moser, Isaac L Molina, Robert Case, Fares Ayoub and 3 more

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Article in Gastro hep advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Vikas J PatelDivision of Gastroenterology, Hepatology and Nutrition, University of Florida College of Medicine, Gainesville, Florida.
Maher HomsiDivision of Gastroenterology, Hepatology and Nutrition, University of Florida College of Medicine, Gainesville, Florida.
Nicholas A OrriolsDivision of Gastroenterology, Hepatology and Nutrition, University of Florida College of Medicine, Gainesville, Florida.
Naueen A ChaudhryDivision of Gastroenterology, Hepatology and Nutrition, University of Florida College of Medicine, Gainesville, Florida.
Joseph R GrajoDivision of Abdominal Imaging, Department of Radiology, University of Florida College of Medicine, Gainesville, Florida.
Abdullah MalkawiDivision of Abdominal Imaging, Department of Radiology, University of Florida College of Medicine, Gainesville, Florida.
Patricia MoserDivision of Abdominal Imaging, Department of Radiology, University of Florida College of Medicine, Gainesville, Florida.
Isaac L MolinaDivision of Gastroenterology, Hepatology and Nutrition, University of Florida College of Medicine, Gainesville, Florida.
Robert CaseDepartment of Medicine, University of Florida College of Medicine, Gainesville, Florida.
Fares AyoubDepartment of Medicine, University of Florida College of Medicine, Gainesville, Florida.
Nicholas I KaufmanDepartment of Medicine, University of Florida College of Medicine, Gainesville, Florida.
Tiffany LambrouDepartment of Medicine, University of Florida College of Medicine, Gainesville, Florida.
Ellen M ZimmermannDivision of Gastroenterology, Hepatology and Nutrition, University of Florida College of Medicine, Gainesville, Florida.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aims: Internal fistulas found on cross-sectional imaging (CSI) performed during routine care of patients with Crohn's disease (CD) are often considered incidental findings. This study aimed to assess outcomes in patients with internal fistulas on CSI. Methods: This is a single tertiary care center, retrospective case-control study of CD outcomes. Patients who had magnetic resonance enterography or computer tomography enterography performed between 2007 and 2017 were included. Electronic medical record data up to 2017 were included as variables in logistic regression analysis. CSI was scored by 3 abdominal radiologists blinded to the electronic medical record. Results: Subjects included 199 CD patients: 63 patients (cases) had internal fistulas on index scan and 136 had no internal fistula. The cases and controls were well-matched for age, race, smoking status, body mass index, and years of disease. During follow-up, cases had a more complicated disease course with higher incidence of intra-abdominal abscess formation (19.1% vs 3.7%; Conclusion: CD patients with internal fistulas identified by CSI have worse disease outcomes. Presence of internal fistula is the only independent risk factor for future intra-abdominal abscess regardless of the patient's symptoms.

Indexed as

ComplicationsCrohn’s DiseaseCross-Sectional ImagingFistula

Identifiers

PMID40599561
PMCPMC12209915

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