Evidence map›Paper›PMID 40599544›Full record

ArticleFrontiers in genetics2025

Case Report: Successful late-line pralsetinib treatment in an ALK-rearranged lung adenocarcinoma patient with KIF5B-RET fusion resistant to alectinib.

Feng Jin, Chenyang Wang, Fang Yang, Shubin Wang, Fen Wang

Abstract readCase Reports
In one paragraph

Article in Frontiers in genetics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Feng Jin *Department of Medical Oncology, Peking University Shenzhen Hospital, Shenzhen, China.
Chenyang Wang *Shenzhen University, Shenzhen, China.
Fang YangDepartment of Medical Oncology, Peking University Shenzhen Hospital, Shenzhen, China.
Shubin WangDepartment of Medical Oncology, Peking University Shenzhen Hospital, Shenzhen, China.
Fen WangDepartment of Medical Oncology, Peking University Shenzhen Hospital, Shenzhen, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anaplastic lymphoma kinase (

Indexed as

alectinibALK-rearrangedcase reportKIF5B-RETlung adenocarcinomapralsetinib

Identifiers

PMID40599544
PMCPMC12209176

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.