Evidence map›Paper›PMID 40599502›Full record

ArticleCureus2025

Drug-Induced Pemphigus Foliaceus Potentially Triggered by Piperacillin-Tazobactam, Linezolid, and Additional Factors: A Report of a Rare Case.

Aishwarya Holi, Satya Rijal, Sumugdha Rayamajhi, Nikhil Regmi

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Aishwarya HoliInternal Medicine, Michigan State University College of Human Medicine, East Lansing, USA.
Satya RijalInternal Medicine, Michigan State University College of Human Medicine, East Lansing, USA.
Sumugdha RayamajhiInternal Medicine, Michigan State University College of Human Medicine, East Lansing, USA.
Nikhil RegmiInternal Medicine, Michigan State University College of Human Medicine, East Lansing, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Drug-induced pemphigus (DIP) is a rare autoimmune blistering disorder most commonly associated with thiol-containing drugs such as penicillamine, captopril, and bucillamine. However, additional medications are increasingly recognized in the nonthiol nonphenol group. While some cases require treatment with corticosteroids or immunosuppressants, in certain instances, simply discontinuing the offending drug is sufficient. We report a unique case of drug-induced pemphigus foliaceus (DIPF) potentially triggered by piperacillin-tazobactam and/or linezolid in a 69-year-old female patient on the 10th day of hospitalization while receiving treatment for necrotizing fasciitis and

Indexed as

bullous skin lesionsdesmogleindrug-induced pemphiguspemphigus foliaceouspemphigus triggers

Identifiers

PMID40599502
PMCPMC12208815

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.