Evidence map›Paper›PMID 40599494›Full record

ArticleOpen forum infectious diseases2025

Clinician Management Preferences for

Noah Boton, Payal K Patel, Susan E Beekmann, Philip M Polgreen, Whitney R Buckel, Monica V Mahoney, Preeti Mehrotra, Matthew S L Lee

Abstract read
In one paragraph

Article in Open forum infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Noah BotonDivision of Infectious Diseases and Immunology, NYU Langone Health, New York, New York, USA.ORCID https://orcid.org/0000-0002-2917-5125
Payal K PatelDivision of Infectious Diseases, Intermountain Health, Salt Lake City, Utah, USA.
Susan E BeekmannDepartment of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA.ORCID https://orcid.org/0000-0003-0278-506X
Philip M PolgreenDepartment of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA.
Whitney R BuckelPharmacy Services, Intermountain Health, Taylorsville, Utah, USA.ORCID https://orcid.org/0000-0001-9505-2572
Monica V MahoneyDepartment of Pharmacy, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0002-5071-2159
Preeti MehrotraDivision of Infectious Diseases, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.
Matthew S L LeeDivision of Infectious Diseases, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0002-3186-2020

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The 2021 Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA) guidelines for Methods: An electronic survey was distributed to members of the IDSA Emerging Infections Network in May 2024, targeting ID physicians and healthcare professionals in the United States who manage adult CDI. The survey assessed treatment preferences, clinical practices, and barriers to accessing and prescribing CDI therapies. Results: Of the 500 respondents who reported treating CDI in the past year, 83% (417/500) indicated that vancomycin was their most frequently prescribed agent for initial, nonfulminant CDI. Additionally, 72% (357/498) reported that their institutional guidelines recommended vancomycin as the first-line agent. The most common barrier to fidaxomicin use was challenges with outpatient insurance coverage (82% [408/496]). Bezlotoxumab was available to 74% (370/500) of respondents, though 33% (165/497) indicated they do not use bezlotoxumab routinely. Most clinicians (87% [437/500]) had previously recommended fecal microbiota transplantation (FMT) for recurrent CDI, though only 48% (239/500) had current access to FMT using donor stool. Fecal microbiota live-jslm was available to 36% (179/500), and fecal microbiota spores live-brpk was available to 30% (150/500). Conclusions: Significant barriers, including high costs, insurance challenges, and limited availability of CDI therapies, impact clinical decision-making and adherence to guideline recommendations.

Indexed as

CDIClostridioides difficile infectionguidelinesinfectious diseases clinicianssurvey

Identifiers

PMID40599494
PMCPMC12207967

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.