Evidence map›Paper›PMID 40599457›Full record

ArticleArchives of Razi Institute2024

Breast cancer - Clinicopathological profile at a Tertiary Cancer Center in India.

McS Babu, A Choudhary, L A Jacob, K N Lokesh, A H Rudresha, L K Rajeev, S Saldanha, T Begum

Abstract read
In one paragraph

Article in Archives of Razi Institute, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

McS BabuDepartment of Medical Oncology, Kidwai Memorial Institute of Oncology, Bengaluru- 560029, India.
A ChoudharyDepartment of Medical Oncology, Kidwai Memorial Institute of Oncology, Bengaluru- 560029, India.
L A JacobDepartment of Medical Oncology, Kidwai Memorial Institute of Oncology, Bengaluru- 560029, India.
K N LokeshDepartment of Medical Oncology, Kidwai Memorial Institute of Oncology, Bengaluru- 560029, India.
A H RudreshaDepartment of Medical Oncology, Kidwai Memorial Institute of Oncology, Bengaluru- 560029, India.
L K RajeevDepartment of Medical Oncology, Kidwai Memorial Institute of Oncology, Bengaluru- 560029, India.
S SaldanhaDepartment of Medical Oncology, Kidwai Memorial Institute of Oncology, Bengaluru- 560029, India.
T BegumDepartment of Medical Oncology, Kidwai Memorial Institute of Oncology, Bengaluru- 560029, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The demographic characteristics of breast cancer patients from disparate geographical regions vary considerably. Accordingly, the objective of this study was to present the clinicopathological features of breast cancer patients at our center and to conduct a comparative analysis with the findings of other studies. This retrospective descriptive study, which included 816 patients registered in the two years between October 2021 and September 2023, was conducted in the Department of Medical Oncology at a government tertiary cancer care center in southern India. At the initial presentation, the median age was 49 years, with the majority of patients being postmenopausal. The most common presenting complaint was a breast lump, which was reported in 636 cases (77.9%). Additionally, 115 cases (14.09%) involved axillary edema. A family history of breast cancer was evident in 19.9% (162/816) of the patients. Of the patients, 594 (72.8%) exhibited hormone receptor positivity. Of the total number of cases, 202 (nearly 25%) were positive for HER2/neu by FISH or IHC. A total of 178 patients (21.9%) were diagnosed with triple-negative breast cancer (TNBC). The majority of patients (46.8%) presented at a late stage, classified as Stage III. In cases of stage IV disease, there was a greater prevalence of skeletal metastases (40.3%) compared to visceral metastases. The present study offers insight into the current state of breast cancer patients in Southern India. The majority of patients were postmenopausal. Additionally, there has been an observed increase in the number of patients with hormone receptor-positive tumors, accompanied by a higher prevalence of metastatic disease involving skeletal metastasis compared to other sites. It is imperative to enhance awareness about breast cancer, assuage apprehensions, and disseminate information about the significance of screening, prompt diagnosis, and treatment. Such studies provide a foundation for understanding the extent of the problem and facilitate the identification of potential solutions.

Indexed as

Breast NeoplasmsAdultAgedAged, 80 and overFemaleHumansIndiaMiddle AgedRetrospective StudiesTertiary Care CentersYoung AdultBreast CancerCommon CancerEpidemiology Breast CancerFemale CancerIndian Cancer

Identifiers

PMID40599457
PMCPMC12207961

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