Evidence map›Paper›PMID 40599395›Full record

ArticleInternational journal of nanomedicine2025

Monitoring the Antibacterial Activity of the Green Synthesized ZnO Nanoparticles on the Negative and Positive Gram Bacteria Mimicking Oral Environment by Using a Quartz Tuning Fork (QTF) Micromechanical Sensor.

Khalid A Al-Hamad, Ashwaq Asiri, Ali M Alqahtani, Saud Alotaibi, Abdullah Almalki

Abstract read
In one paragraph

Article in International journal of nanomedicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Nanosponge-integrated hydrogel ofFrontiers in pharmacology · 2026
    Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Khalid A Al-HamadDepartment of Maxillofacial and Diagnostic Sciences, College of Dentistry, Majmaah University, Majmaah, 11952, Saudi Arabia.ORCID 0000-0003-2789-9127
Ashwaq AsiriDepartment of Restorative Dental Sciences, College of Dentistry, Majmaah University, Majmaah, 11952, Saudi Arabia.
Ali M AlqahtaniDepartment of Diagnostic Dental Sciences, College of Dentistry, King Khalid University, Abha, 62529, Saudi Arabia.
Saud AlotaibiDepartment of Preventive Dental Sciences, College of Dentistry, Majmaah University, Majmaah, 11952, Saudi Arabia.ORCID 0000-0002-4544-5631
Abdullah AlmalkiDepartment of Preventive Dental Sciences, College of Dentistry, Majmaah University, Majmaah, 11952, Saudi Arabia.ORCID 0000-0002-3064-3547

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Green-synthesized nanoparticles show promise as anti-biofilm and antibacterial agents in medical applications, including dental implants and oral devices. However, conventional antibacterial testing methods are laborious and lack sensitivity. Quartz tuning fork (QTF)-based biosensors offer a compelling alternative due to their high sensitivity, compact size, and cost-effectiveness. This study evaluates a QTF biosensor for quantifying the antibacterial activity of green-synthesized ZnO nanoparticles against negative and positive Gram bacteria. Methods: The antibacterial activity of ZnO nanoparticles was tested in a simulated oral environment against Results: The QTF biosensor detected significant antibacterial activity as resonance frequency decreased by 5.69 ± 3.81 hz ( Discussion: The QTF biosensor successfully quantified the antibacterial effects of green-synthesized ZnO nanoparticles, demonstrating its potential as a rapid, sensitive alternative to traditional methods. The differential responses of

Indexed as

Anti-Bacterial AgentsBiosensing TechniquesMetal NanoparticlesNanoparticlesZinc OxideEscherichia coliGreen Chemistry TechnologyMicrobial Sensitivity TestsMouthQuartzStaphylococcus aureusAnti-Bacterial AgentsQuartzZinc Oxideantibacterialpositive and negative gram bacteriaQTFZnO nanoparticles

Identifiers

PMID40599395
PMCPMC12209601

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.