ArticleStructural heart : the journal of the Heart Team2025
Novel Technique Employing Transcatheter Balloon-Expandable Valves in Pure Aortic Regurgitation: A Proof-of-Concept Study.
Article in Structural heart : the journal of the Heart Team, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed.
- Rescue Transcatheter Aortic Valve Implantation for Severe Native Aortic Regurgitation in a Young Patient with Hypertrophic Obstructive Cardiomyopathy and Cardiogenic Shock: Review of the Literature and Case Presentation.Life (Basel, Switzerland) · 2026Review
- Securing the Anchor in Pure Native Aortic Regurgitation: Innovations, Techniques, or Dedicated Devices?JACC. Case reports · 2026Article
- Transcatheter Aortic Valve Replacement in a Failed Homograft.JACC. Case reports · 2026Article
- How to Plan a Transcatheter Aortic Valve Replacement in a Failed Aortic Homograft.JACC. Case reports · 2026Article
- Editorial: Reviews in transcatheter aortic valve implantation.Frontiers in cardiovascular medicine · 2025Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The aim of this study was to evaluate the hypothesis that employing the "flare the outflow" technique might allow anchoring of transcatheter balloon-expandable valves (BEVs) in patients with pure aortic regurgitation. Methods: This was a single-center, 6-patient, consecutive, retrospective observational cohort. Inoperable patients with pure AR were included to perform transcatheter aortic valve implantation. The technique involved deploying BEVs with 2-mm oversizing and "flare the outflow" technique. Computed tomography scans were obtained at baseline and after implantation. Results: BEVs with the flared outflow were successfully implanted in all patients. All patients were discharged without device migration and none or trace paravalvular leak. At 1-year follow-up, no deaths, valve dysfunction, or reinterventions were observed. Among the 5 patients out of 6 who underwent follow-up computed tomography scans, findings confirmed the overexpanded outflow of the BEVs compared to the annulus, indicated by mean (24.5 vs. 23.3 mm, Conclusions: The utilization of BEVs incorporating the "flare the outflow" technique demonstrated feasibility and effectiveness in inoperable patients with pure AR. Further studies are required to determine the durability and lifetime management associated with this technique.
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