[Survey of Compliance With ARRIVE Guidelines in Medical Research Papers in Chinese].

Objective: To evaluate the current status of compliance with animal experiment reporting guidelines in medical research papers published in Chinese and to enhance the transparency of medical research reporting. Methods: Using a predefined literature search strategy, we conducted searches in the Results: A total of 4818 research papers were included in the analysis, and none comprehensively reported all 22 pieces of information investigated in the study. Most of the research papers published in 2019 and 2022 reported information on the control groups, with the reporting rate for the respective years being 99.8% (2461/2467) and 99.7% (2343/2351). Although the sample size reporting rates were 79.2% (1954/2467) for research papers published in 2019 and 77.2% (1815/2351) for those published in 2022, none described the method and rationale of sample size calculation. The reporting rates of randomisation and blinding methods were approximately 20% and 1%, respectively. The reporting of statistical methods increased slightly from 91.8% in 2019 to 96.0% in 2022. The reporting of information on the experimental animals showed mixed trends for 2019 and 2022, including the provenance of animals (93.8% vs. 93.7%, Conclusions: Since ARRIVE Guidelines 2.0 was released, transparency in the reporting of most of the ARRIVE checklist items of interest in this study has improved significantly. However, the reporting of randomization, blinding, ethical statement, and declaration of interests still need further improvement and should be prioritized for future efforts.