[Preliminary Study of Dilated Cardiomyopathy at a High Altitude Based on Cardiac Magnetic Resonance Feature Tracking].

Objective: To investigate the application of cardiovascular magnetic resonance feature tracking (CMR-FT) in assessing myocardial strain in dilated cardiomyopathy (DCM) patients residing at high altitudes. Methods: We retrospectively enrolled 29 DCM patients living at high altitudes (DCM-H), 27 DCM patients living in a low-altitude plain environment (DCM-P), 23 healthy volunteers living at a high altitude (HV-H), and 24 healthy volunteers living in a low-altitude plain environment (HV-P). All subjects underwent cine MRI scanning using a 3.0T rapid steady-state free precession sequence. The CMR images thus acquired were analyzed using cvi42, a post-processing software, to obtain left ventricular function and myocardial strain parameters. Results: Compared with the HV-H group, the DCM-H group showed higher left ventricle end-diastolic volume (LVEDV) and left ventricle end-systolic volume (LVESV), and lower left ventricular ejection fraction (LVEF) and stroke volume ( LVSV) (all Conclusion: Myocardial strain in DCM patients living at a high altitude is lower than that in healthy volunteers living at a high altitude, but higher than that in DCM patients living in a low-altitude plain environment. CMR-FT can be used to quantitatively assess myocardial contractility in DCM patients living at a high altitude, showing promise for clinical application.