Evidence map›Paper›PMID 40599293›Full record

Trial reportSichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition2025

[Esketamine Alleviates Postoperative Depressive Symptoms in Frail Elderly Patients Undergoing Thoracoscopic Radical Resection of Lung Cancer: A Randomized Double-Blind Controlled Trial].

Congli Zhang, Yan Yan, Junjie Ma, Ke Wang, Di Liu, Yang Zhang, Xiaohong Li, Li Ren

Abstract readRandomized Controlled TrialEnglish Abstract
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Congli Zhang（ 233004） Department of Anesthesiology, The First Affiliated Hospital of Bengbu Medical University, Bengbu 233004, China.
Yan Yan（ 233004） Department of Anesthesiology, The First Affiliated Hospital of Bengbu Medical University, Bengbu 233004, China.
Junjie Ma（ 233004） Department of Anesthesiology, The First Affiliated Hospital of Bengbu Medical University, Bengbu 233004, China.
Ke Wang（ 233004） Department of Anesthesiology, The First Affiliated Hospital of Bengbu Medical University, Bengbu 233004, China.
Di Liu（ 233004） Department of Anesthesiology, The First Affiliated Hospital of Bengbu Medical University, Bengbu 233004, China.
Yang Zhang（ 233004） Department of Anesthesiology, The First Affiliated Hospital of Bengbu Medical University, Bengbu 233004, China.
Xiaohong Li（ 233004） Department of Anesthesiology, The First Affiliated Hospital of Bengbu Medical University, Bengbu 233004, China.
Li Ren（ 233004） Department of Anesthesiology, The First Affiliated Hospital of Bengbu Medical University, Bengbu 233004, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To investigate the effect of esketamine on postoperative depression in frail elderly patients undergoing thoracoscopic radical resection of lung cancer. Methods: A total of 88 frail elderly patients undergoing elective thoracoscopic radical resection of lung cancer were assigned randomly (using a randomization table) and in a double-blind way (blinding applies to both researchers and patients) to an esketamine group (Esk group, Results: Three patients were excluded from the Esk group and the NS group, respectively, and eventually, 41 patients in each group were included in the statistical analysis. There were no statistically significant differences between the two groups in terms of age, sex, body mass index, American Society of Anesthesiologists (ASA) classification, comorbidities, educational attainment, and the scores for HAMD-17, PSQI, and MMSE 1 day before surgery ( Conclusion: Esketamine can improve the postoperative depressive state, sleep quality, and cognitive function in frail elderly patients undergoing thoracoscopic radical resection of lung cancer.

Indexed as

DepressionKetamineLung NeoplasmsPostoperative ComplicationsThoracoscopyAgedAged, 80 and overDouble-Blind MethodFemaleHumansMaleEsketamineKetamineEsketamineFrail elderly patientsPostoperative depressive stateRadical resection of lung cancerThoracoscopy

Identifiers

PMID40599293
PMCPMC12207054

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.