Evidence map›Paper›PMID 40599261›Full record

ArticleEnvironmental science & technology letters2025

Elevated PFAS Precursors in Septage and Residential Pump Stations.

Michael Penrose, Jacob Deighton, Susan T Glassmeyer, Andrew Brougham, Scott M Bessler, Taryn Mcknight, Mohamed Ateia

Abstract read
In one paragraph

Article in Environmental science & technology letters, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Michael PenroseORISE Participant at Center for Environmental Solutions & Emergency Response, U.S. Environmental Protection Agency, Cincinnati, Ohio 45220, United States.
Jacob DeightonMetropolitan Sewer District of Greater Cincinnati, Cincinnati, Ohio 45204, United States.
Susan T GlassmeyerCenter for Environmental Solutions & Emergency Response, U.S. Environmental Protection Agency, Cincinnati, Ohio 45220, United States.ORCID https://orcid.org/0000-0002-0538-5793
Andrew BroughamMetropolitan Sewer District of Greater Cincinnati, Cincinnati, Ohio 45204, United States.
Scott M BesslerMetropolitan Sewer District of Greater Cincinnati, Cincinnati, Ohio 45204, United States.
Taryn McknightEurofins Environment Testing, West Sacramento, California 95605, United States.
Mohamed AteiaCenter for Environmental Solutions & Emergency Response, U.S. Environmental Protection Agency, Cincinnati, Ohio 45220, United States; Department of Chemical and Biomolecular Engineering, Rice University, Houston, Texas 77251, United States.ORCID https://orcid.org/0000-0002-3524-5513

Funding

Intramural EPA EPA999999
6 · The paper itself

Abstract

Residential wastewater, with no industrial inputs, is an underrecognized source of per- and polyfluoroalkyl substances (PFAS). This study provides the first direct comparison of PFAS in septage and pump stations, targeting 70 PFAS compounds and employing the total oxidizable precursor (TOP) assay. Septage exhibited markedly higher PFAS and precursors concentrations than pump stations, with median post-TOP levels of 687.5 ng/L vs 84.2 ng/L, respectively. FTCAs were fully oxidized, while diPAPs showed incomplete oxidation due to high organic loads. Septic systems function as PFAS reservoirs, increasing risks of groundwater contamination, particularly in areas with shallow aquifers. Pump stations contributed to episodic PFAS spikes, likely affecting downstream wastewater treatment. The detection of 27 PFAS compounds, including short-chain alternatives, highlights shifting contamination patterns. Findings emphasize the need for tailored analytical frameworks and pretreatment technologies to mitigate PFAS risks across decentralized and centralized wastewater systems. Integrating precursor analysis is critical for accurate risk assessment, as targeted PFAS measurements underestimate contamination. These results provide new insights into PFAS behavior in residential wastewater, guiding future mitigation efforts.

Indexed as

municipal wastewaterPFASseptageseptic systemsTOP assay

Identifiers

PMID40599261
PMCPMC12207394

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.