Evidence map›Paper›PMID 40599260›Full record

ArticleMacromolecules2024

High Molecular Weight Protein-Like Semiflexible Chains via Bioorthogonal Polymerization of Coiled-Coil Peptides.

Hanyuan Gao, Tianren Zhang, Matthew G Langenstein, Weiran Xie, Samiksha Udan, Zihan Zhang, Jeffery G Saven, Shi Bai, Darrin J Pochan, Joseph M Fox and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Macromolecules, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Hanyuan GaoDepartment of Materials Science and Engineering, University of Delaware, Newark, DE, 19716, USA.
Tianren ZhangDepartment of Materials Science and Engineering, University of Delaware, Newark, DE, 19716, USA.
Matthew G LangensteinDepartment of Materials Science and Engineering, University of Delaware, Newark, DE, 19716, USA.
Weiran XieDepartment of Materials Science and Engineering, University of Delaware, Newark, DE, 19716, USA.
Samiksha UdanDepartment of Materials Science and Engineering, University of Delaware, Newark, DE, 19716, USA.
Zihan ZhangDepartment of Materials Science and Engineering, University of Delaware, Newark, DE, 19716, USA.
Jeffery G SavenDepartment of Chemistry, University of Pennsylvania, Philadelphia, PA, 19104, USA.
Shi BaiDepartment of Chemistry and Biochemistry, University of Delaware, Newark, DE, 19716, USA.
Darrin J PochanDepartment of Materials Science and Engineering, University of Delaware, Newark, DE, 19716, USA.
Joseph M FoxDepartment of Materials Science and Engineering, University of Delaware, Newark, DE, 19716, USA.
Xinqiao JiaDepartment of Materials Science and Engineering, University of Delaware, Newark, DE, 19716, USA.

Funding

A Hydrogel-Based Cellular Model of the Human Vocal FoldR01DC014461 · NIDCD · UNIVERSITY OF DELAWARE · PI Xinqiao Jia · 2016 to 2026
$6.2M
Research Supplements to Promote Diversity in Health-Related Research (Admin Supp)R01DE029655 · NIDCR · UNIVERSITY OF DELAWARE · PI Xinqiao Jia · 2021 to 2026
$2.8M
NIDCD NIH HHS R01 DC014461NIDCR NIH HHS R01 DE029655
6 · The paper itself

Abstract

Peptides capable of forming homotetrameric coiled-coil bundles are utilized as the monomeric building blocks ("bundlemers") to synthesize protein-like hybrid polymers consisting of covalently linked coiled-coil microdomains with regularly spaced ethylene glycol repeats via step-growth polymerization employing the highly efficient, bioorthogonal tetrazine (Tz) ligation with

Indexed as

Coiled-coil peptidesentanglementmolecular weightsemiflexiblestep growth polymerizationtetrazine ligation

Identifiers

PMID40599260
PMCPMC12208629

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.