Evidence map›Paper›PMID 40599225›Full record

ArticleAfrican journal of emergency medicine : Revue africaine de la medecine d'urgence2025

Characteristics and outcomes of children initiated on high flow nasal cannula and continuous positive airway pressure at the emergency centre of a district hospital in South Africa.

Jessica Head, Andrew Redfern, Jana Hoole, Liezl Ulbrich, Refilwe More, Daniël J van Hoving, Eric D McCollum, Shubhada Hooli

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Article in African journal of emergency medicine : Revue africaine de la medecine d'urgence, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Jessica HeadDepartment of Paediatrics, Khayelitsha Hospital, Cape Town, South Africa.
Andrew RedfernDepartment of Paediatrics & Child Health, Stellenbosch University, Cape Town, South Africa.
Jana HooleDepartment of Paediatrics, Khayelitsha Hospital, Cape Town, South Africa.
Liezl UlbrichWestern Cape Government Emergency Medical Services, Cape Town, South Africa.
Refilwe MoreDepartment of Paediatrics & Child Health, Stellenbosch University, Cape Town, South Africa.
Daniël J van HovingDivision of Emergency Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.
Eric D McCollumHealth Systems Program, Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Shubhada HooliGlobal Program in Pediatric Respiratory Sciences, Eudowood Division of Pediatric Respiratory Sciences, Department of Pediatrics, Johns Hopkins School of Medicine, Baltimore, MD, USA.

Funding

Pulse Oximetry Accuracy and Integration into Pediatric Outpatient Care in South AfricaK23HL169901 · NHLBI · BAYLOR COLLEGE OF MEDICINE · PI Shubhada Hooli · 2024 to 2026
$552k
NHLBI NIH HHS K23 HL169901
6 · The paper itself

Abstract

Introduction: High-flow nasal cannula (HFNC) and continuous positive airway pressure delivered via a nasal interface (nCPAP) are increasingly used for paediatric emergency care in South Africa. In Cape Town, initiation of HFNC/nCPAP at a district hospital, in most instances, necessitates transfer to a paediatric high-care facility. We sought to describe the population of children initiated on HFNC/nCPAP and their short-term hospital outcomes post interfacility transfer. Methods: The authors conducted a one-year retrospective observational study between August 1st 2021, to July 31st Results: At Khayelitsha Hospital, 117 patients were initiated on HFNC ( Conclusion: Roughly a quarter of patients were weaned from respiratory support within 24 h of transfer. Short term outcomes were good overall, demonstrating safe interfacility transfer and low mortality. Further research is needed to inform practice on best use of HFNC and nCPAP in the emergency care of children presenting with acute respiratory illness in South Africa.

Indexed as

ChildContinuous positive airway pressureHigh flow nasal cannulaLow- and middle-income countriesPneumoniaSouth Africa

Identifiers

PMID40599225
PMCPMC12211819

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.