ArticleJournal of dentistry (Shiraz, Iran)2025
Efficacy of Remineralizing Agents for Prevention of Microhardness Reduction and Change in Mineral Content of Enamel in Anterior Primary Teeth after Exposure to Iron Drop.
Article in Journal of dentistry (Shiraz, Iran), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Assessment of Remineralization Treatment on Primary Enamel's Microhardness and Mineral Composition Post Iron Drop Interaction.International journal of dentistry · 2026Article
- Evaluation of the effectiveness of different remineralization agents on primary and permanent teeth exposed to acidic liquids: a randomized controlled in vitro study.BMC oral health · 2025Article
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Some alterations in the enamel structure of primary teeth have been reported following iron drop consumption. The efficacy of different remineralizing agents for this problem is still challenging. Purpose: This study aimed to assess the efficacy of remineralizing agents for prevention of microhardness reduction and change in primary enamel mineral content after exposure to iron drop. Materials and Method: In this experimental study, 36 sound primary anterior teeth were assigned to four groups of control, casein phosphopeptide amorphous calcium phosphate (CPP-ACP), fluoride varnish (FV), and CPP-ACP+FV (MI varnish). The baseline microhardness of the teeth was first measured by Vickers hardness tester using 50 g load for 10 seconds. Next, the microhardness was measured after remineralizing agents were applied on the specimens. After the application of iron drop for 5 minutes, and pH cycling for 10 days, the final microhardness of specimens was registered. Specimens were also subjected to energy dispersive X-ray spectroscopy (EDS) in the control group, after remineralization and after the application of iron drop. Data were analyzed by one-way ANOVA, Tukey's test, and Tamhane's test. Results: The final microhardness was significantly higher in all remineralized groups compared to the control group ( Conclusion: Application of CPP-ACP, FV, and MI varnish prior to iron drop exposure can improve microhardness. MI varnish had significantly higher efficacy for this purpose than the other two remineralizing agents.
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