Evidence map›Paper›PMID 40599190›Full record

Trial reportWorld journal of gastroenterology2025

Carbonated soft drink for gastric preparation for magnetically controlled capsule endoscopy: An open-label randomized controlled trial.

Jia-Hui Zhu, Xiao Liu, Wei Zhou, Xiao-Nan Xu, Wen-Da Sheng, Yi-Lin Han, Xiao-Ou Qiu, Ya-Wei Liu, Yang-Yang Qian, Zhuan Liao and 1 more

Abstract readComparative StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in World journal of gastroenterology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jia-Hui ZhuDepartment of Gastroenterology and Endoscopy, Eastern Hepatobiliary Surgery Hospital, The Naval Medical University, Shanghai 200438, China.
Xiao LiuDepartment of Digestive Diseases, National Clinical Research Center, Shanghai 200433, China.
Wei ZhouDepartment of Digestive Diseases, National Clinical Research Center, Shanghai 200433, China.
Xiao-Nan XuDepartment of Digestive Diseases, National Clinical Research Center, Shanghai 200433, China.
Wen-Da ShengDepartment of Digestive Diseases, National Clinical Research Center, Shanghai 200433, China.
Yi-Lin HanDepartment of Digestive Diseases, National Clinical Research Center, Shanghai 200433, China.
Xiao-Ou QiuDepartment of Digestive Diseases, National Clinical Research Center, Shanghai 200433, China.
Ya-Wei LiuDepartment of Gastroenterology, The First Medical Center of Chinese PLA General Hospital/Chinese PLA Postgraduate Military Medical School, Beijing 100039, China.
Yang-Yang QianDepartment of Digestive Diseases, National Clinical Research Center, Shanghai 200433, China.
Zhuan LiaoDepartment of Digestive Diseases, National Clinical Research Center, Shanghai 200433, China.
Zhao-Shen LiDepartment of Digestive Diseases, National Clinical Research Center, Shanghai 200433, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe clinical effectiveness of magnetically controlled capsule endoscopy (MCE) is well established. However, problems, such as abdominal distension, insufficient gastric filling, and prolonged gastric retention time, persist with MCE gastric preparations.

aimTo compare gastric filling using a carbonated soft drink with that using pure water during MCE.

methodsWe performed an open-label randomised controlled trial at the Endoscopy Centre of Changhai Hospital in Shanghai. Patients aged 18-80 years, with or without gastrointestinal symptoms, scheduled for MCE were consecutively recruited. Those who provided informed consent were randomly assigned to the carbonated soft drink group (C group) or water group (W group) in a 1:1 ratio. For patients in the W group, 1000 mL of water was ingested to distend the stomach, whereas for patients in the C group, 550 mL of carbonated soft drink was provided, and patients were required to drink quickly while minimising burping. The primary endpoint was the number of patients with a gastric filling score of ≥ 4 within 5 minutes after the capsule entered the stomach.

resultsFrom December 3, 2020 to May 17, 2021, 252 patients (141 men), aged 18-77 years, were assigned to the C (

conclusionCarbonated soft drinks demonstrated superior and more sustained gastric filling compared with those of water alone, with the potential to promote gastric emptying.

Indexed as

Capsule EndoscopyCarbonated BeveragesAdolescentAdultAgedAged, 80 and overChinaFemaleHumansMaleMiddle AgedStomachYoung AdultCarbon dioxideClinical trialGastric emptyingGastric fillingGastric preparationMagnetically controlled capsule endoscopy

Identifiers

PMID40599190
PMCPMC12207560

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.