Evidence map›Paper›PMID 40599049›Full record

ArticlePediatrics international : official journal of the Japan Pediatric Society

Comparison of tidal volume and airway pressure during neonatal resuscitation in mask leaks.

Fumihiko Takatori, Tetsuya Isayama, Shigeharu Hosono, Kiyotaka Iwasaki

Abstract readComparative Study
In one paragraph

Article in Pediatrics international : official journal of the Japan Pediatric Society. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Quality of Bag-Mask Ventilation for Children Before Intubation: Single-Center PICU Pilot Observational Study, 2019-2022.Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2026
    Observational
  3. Comparison of tidal volume and airway pressure during neonatal resuscitation in mask leaks.Pediatrics international : official journal of the Japan Pediatric Society
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Fumihiko TakatoriCooperative Major in Advanced Biomedical Sciences, Joint Graduate School of Tokyo Women's Medical University and Waseda University, Waseda University, Tokyo, Japan.ORCID https://orcid.org/0009-0006-8196-5462
Tetsuya IsayamaDivision of Neonatology, National Center for Child Health and Development, Tokyo, Japan.
Shigeharu HosonoDivision of Neonatology, Jichi Medical University Saitama Medical Center, Saitama, Japan.ORCID https://orcid.org/0000-0002-5319-6153
Kiyotaka IwasakiCooperative Major in Advanced Biomedical Sciences, Joint Graduate School of Tokyo Women's Medical University and Waseda University, Waseda University, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundProviding positive-pressure ventilation (PPV) to the lungs is essential for neonatal resuscitation. Accurate PPV requires a precise measurement of tidal volume and airway pressure, with airway obstruction and mask leakage being the primary concerns for ineffective ventilation. This study aimed to investigate the differences between tidal volume and airway pressure measured by a respiratory function monitor (RFM) and the actual values delivered to the lungs in scenarios involving mask leaks, using a system comprising a PPV device, a face mask, and an artificial lung model.

methodsThree experiments were conducted to assess mask leakage (1) under varying lung conditions, (2) under different ventilation rates, and (3) using different PPV devices. Two RFMs were used, one in the test lung and the other in the mask. Trends in those data were assessed by means of a correlation graph.

resultsMask leakage resulted in an underestimation of the actual tidal volume, with the effect intensifying as the leak percentage increased. PPV devices using a compressed gas source demonstrated less reduction in lung tidal volume (from 15 to 12 mL) owing to mask leaks compared with those without such a source (from 16 to 5 mL).

conclusionsSignificant discrepancies were observed between RFM readings and test lung values for tidal volume. These findings highlight the importance of accurate monitoring to prevent lung injury caused by excessive tidal volume, particularly in the presence of mask leaks. Accurately measuring tidal volume in the presence of mask leaks presents a significant challenge for the future.

Indexed as

MasksPositive-Pressure RespirationResuscitationTidal VolumeEquipment FailureHumansInfant, NewbornRespiratory Function Testsinfant newbornpositive‐pressure respirationresuscitation

Identifiers

PMID40599049
PMCPMC12215236

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.