Evidence map›Paper›PMID 40599040›Full record

Trial reportThe Journal of dermatology2025

Use of 5% Topical Minoxidil Application for Telogen Effluvium: An Open-Label Single-Arm Clinical Trial.

Manabu Ohyama, Ryokichi Irisawa, Masaki Uchiyama, Miho Mori, Kazuhiro Aoki, Yuto Ueda, Toru Fujita

Abstract readClinical Trial
In one paragraph

Trial report in The Journal of dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Manabu OhyamaDepartment of Dermatology, Kyorin University School of Medicine, Tokyo, Japan.ORCID https://orcid.org/0000-0002-2662-5717
Ryokichi IrisawaDepartment of Dermatology, Tokyo Medical University, Tokyo, Japan.
Masaki UchiyamaDepartment of Dermatology, Tokyo Medical University, Tokyo, Japan.
Miho MoriDepartment of Dermatology, Tokyo Medical University, Tokyo, Japan.ORCID https://orcid.org/0000-0001-9923-5157
Kazuhiro AokiClinical Development, Self-Medication, Taisho Pharmaceutical co., Ltd., Tokyo, Japan.ORCID https://orcid.org/0009-0004-2150-5291
Yuto UedaClinical Development, Self-Medication, Taisho Pharmaceutical co., Ltd., Tokyo, Japan.
Toru FujitaClinical Development, Self-Medication, Taisho Pharmaceutical co., Ltd., Tokyo, Japan.

Funding

Taisho Pharmaceutical Co.
6 · The paper itself

Abstract

Telogen effluvium (TE) is an acute and diffuse hair loss due to an abnormal increase in telogen hair follicles in response to external or internal factors. Recently, TE attracts global interest as a major cause of hair loss as a sequela of COVID-19. Typically, hair shedding in TE is expected to cease around 3-6 months from the onset with spontaneous hair regrowth, once the triggering factor is eliminated. However, the substantial shedding causes heavy psychological stress on patients, and there is no evidence-based treatment. To assess the usefulness of topical minoxidil, which has been reported to improve the hair cycle, for TE, an open-label, single-arm clinical trial was conducted enrolling 12 Japanese subjects (3 men and 9 women) who were diagnosed as TE by experts. For each subject, 1 mL of 5% topical minoxidil lotion was applied to the entire scalp twice daily for 24 weeks. Phototrichogram detected that the terminal hair (≥ 60 μm in diameter) count markedly increased respectively by 12.55 ± 4.99 hairs/cm

Indexed as

AlopeciaCOVID-19MinoxidilAdministration, CutaneousAdministration, TopicalAdultFemaleHairHair FollicleHumansMaleMiddle AgedSARS-CoV-2Skin CreamTreatment OutcomeMinoxidilCOVID‐19hair sheddingpsychological stresstelogen effluviumtopical minoxidil

Identifiers

PMID40599040
PMCPMC12411807

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.