Evidence map›Paper›PMID 40598732›Full record

ArticleCurrent medical imaging2025

Evaluating Cerebral Blood Flow among Patients Experiencing Premenstrual Syndrome with Headache using Duplex Ultrasonography.

Pinar Cakmak, Özlem Kosar Can, Ahmet Baki Yagci

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Article in Current medical imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Pinar CakmakDepartment of Radiology, Pamukkale University, Faculty of Medicine, Denizli, Turkey.ORCID 0000-0003-4652-6748
Özlem Kosar CanDepartment of Obstetrics and Gynecology, Pamukkale University, Faculty of Medicine, Denizli, Turkey.ORCID 0000-0001-7101-4838
Ahmet Baki YagciDepartment of Radiology, Pamukkale University, Faculty of Medicine, Denizli, Turkey.ORCID 0000-0001-7544-5731

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThis study aimed to demonstrate the relationship between hemodynamic changes in head blood flow and headache during the premenstrual period in patients experiencing premenstrual syndrome.

methodsThirty-two female patients experiencing premenstrual headaches were prospectively examined using carotid and vertebral artery duplex ultrasonography during headache episodes in the premenstrual periods and headache-free periods across two consecutive menstrual cycles. The diameters and areas of both the carotid and vertebral arteries, along with systolic and end-diastolic velocities, pulsatility and resistivity indices, and volumetric flow rates, were measured using grayscale imaging. Total head blood flow was determined as the sum of bilateral common carotid artery and vertebral artery flow volumes. Measurements were compared between participants' premenstrual and menstrual periods.

resultsA statistically significant difference in the diameter of the left external carotid artery was observed between periods with and without headache during the two consecutive menstrual cycles assessed ( DISCUSSION: Towards the end of the luteal phase, the total head blood flow and external carotid artery flow were high due to a decrease in peripheral resistance caused by the decline in progesterone and hormonal fluctuations during this period.

conclusionIncreased flow volume in the external carotid arteries and total head blood flow may be a contributing factor to premenstrual headaches.

Indexed as

Cerebrovascular CirculationHeadachePremenstrual SyndromeUltrasonography, Doppler, DuplexAdultBlood Flow VelocityCarotid ArteriesFemaleHumansProspective StudiesVertebral ArteryYoung AdultCarotid arteriesDuplex ultrasoundDysmenorrheaHeadachePremenstrual syndromeUltrasound.

Identifiers

PMID40598732
PMCPMC13181194

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.