Evidence map›Paper›PMID 40598569›Full record

ArticleAntimicrobial resistance and infection control2025

Preventing outbreaks in burn units: the role of hygiene compliance and early warning systems.

Marie Lindblad, Fredrik Huss, Eva Tano, Birgitta Lytsy, Susanne Sütterlin

Abstract read
In one paragraph

Article in Antimicrobial resistance and infection control, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Marie LindbladDepartment of Surgical Sciences, Plastic Surgery, Uppsala University, Uppsala, Sweden. marie.lindblad@uu.se.
Fredrik HussDepartment of Surgical Sciences, Plastic Surgery, Uppsala University, Uppsala, Sweden.
Eva TanoDepartment of Medical Sciences, Section of Clinical Microbiology, Uppsala University, Uppsala, Sweden.
Birgitta LytsyDepartment of Laboratory Medicine, Division of Clinical Microbiology, Karolinska Institute, Stockholm, Sweden.
Susanne SütterlinDepartment of Women´S and Children´S Health, Paediatric Inflammation, Metabolism and Child Health Research International Maternal and Child Health, Uppsala University, Uppsala, Sweden.

Funding

Vetenskapsrådet 2019-05909
6 · The paper itself

Abstract

BACKGROUND AND

objectivesTo analyse observations of staff's hand hygiene, usage of gloves and plastic aprons, and dress code compliance at the Burn Centre, Uppsala University Hospital in Sweden, and to evaluate the association between hygiene non-compliance and outbreak periods. Furthermore, to explore the potential of using routine hygiene observations as an early warning tool for the risk of uncontrolled spread of (multidrug-resistant) bacteria.

methodsDirect observations of the personnel's compliance with hand hygiene, usage of gloves and plastic aprons, and dress code were studied in relation to two A. baumannii outbreaks in 2014 and 2020. Interrupted time series analyses were conducted from 2013 to 2017 and 2018 to 2022 to evaluate outbreak intervention measures. Rolling sums of observed hygiene errors and 90th percentiles were calculated for four-, five-, and six-month periods.

resultsDuring the study, 13,216 direct observations showed hygiene compliance ranging from 70 to 100% per category. Infection control interventions significantly reduced non-compliance after both outbreaks, with sustained improvements for two years following the first outbreak. Rolling four- to six-month sums, using 90th percentile thresholds of seven, nine, and eleven non-compliances predicted A. baumannii outbreaks.

conclusionIn this setting, compliance levels above 97% were consistently observed during outbreak-free periods, suggesting a potential protective effect. Focus on non-compliance as a key metric and rolling sums of non-compliance, may support early detection of increased outbreak risk and guide preventive interventions.

Indexed as

Burn UnitsCross InfectionDisease OutbreaksGuideline AdherenceInfection ControlHand HygieneHumansInterrupted Time Series AnalysisSwedenAcinetobacter baumanniiHygiene errorsOutbreak control

Identifiers

PMID40598569
PMCPMC12210931

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.