ArticleThrombosis journal2025
Red cell distribution width-standard deviation to albumin ratio and mortality in acute pulmonary thromboembolism: a single-center retrospective cohort study.
Article in Thrombosis journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Nomogram-Based Mortality Prediction in Acute Pulmonary Embolism Using Inflammatory Biomarkers and the Simplified Pulmonary Embolism Severity Index.Journal of clinical medicine · 2026Article
- Serum Albumin as a Predictor of Pulmonary Embolism Severity: A Retrospective Study From Buraydah, Saudi Arabia.Cureus · 2026Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRecent studies have shown a relation between red blood cell distribution width (RDW) / albumin (RAR) levels and worse outcomes in cases of pulmonary embolism (PE). Simplified pulmonary embolism severity index (sPESI) has been developed from more complex PESI score, predicting the risk of death in patients with acute PE (APE). This study aims to investigate whether RDW-Standard Deviation/Albumin (RDW-SD/Alb) can serve as a useful prognostic marker for APE and enhance the predictive capability of the sPESI.
methodsThis research is a single-center, retrospective analysis involving patients over 18 years. We enrolled 235 consecutive hospitalized patients with confirmed APE diagnoses. To evaluate the sensitivity and specificity of RDW-SD/Alb, sPESI, and the combined sPESI plus RDW-SD/Alb in predicting 6-month all-cause death, we used Receiver Operating Characteristic (ROC) curves. Additionally, we conducted Kaplan-Meier analysis to assess the impact of elevated RDW-SD/Alb levels (> 13.6) on patient survival time. We utilized multivariate Cox regression analysis to identify independent prognostic factors affecting patients survival.
resultsThe mortality rate for RDW-SD/Alb > 13.6 group was significantly higher than that for the RDW-SD/Alb ≤ 13.6 group. Area under ROC (AUROC) of sPESI plus RDW-SD/Alb was statistically larger than AUROC of sPESI (p = 0.025). In the fully adjusted model, increased RDW-SD/Alb levels were consistently linked to all-cause mortality within six months of admission.
conclusionsThe predictive value of the sPESI for 6-month all-cause death improved when the RDW-SD/Alb > 13.6 parameter was included. RDW-SD/Alb, a novel inflammatory marker, was an independent prognostic factor for predicting 6-month all-cause mortality in patients with APE.
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