Evidence map›Paper›PMID 40598473›Full record

ArticleBiomarker research2025

Diagnostic value of the wnt target and cancer-associated blood biomarker hPG80: ONCOPRO case-control prospective study.

Benoit You, Sebastien Couraud, Philippe Ceruse, Lionel Badet, Philippe Paparel, Alice Durand, Marielle Guillet, Philippe Merle, Gaelle Lescuyer, Charles-André Philip and 16 more

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomarker research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03787056 (Predictive Value of Progastrin Titer at Diagnosis and of Progastrin Kinetics During Treatment in Cancer Patients), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03787056 narecruitingnot on this map

Predictive Value of Progastrin Titer at Diagnosis and of Progastrin Kinetics During Treatment in Cancer Patients

TypeinterventionalSponsorHospices Civils de LyonRan2018 to 2028Enrolled410ConditionsCancer, Breast Cancer, Gastric Cancer, Renal CancerArmsBlood draws
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors.

Benoit YouLyon University Hospital, IC-HCL, Lyon University, Lyon, France. benoit.you@chu-lyon.fr.
Sebastien CouraudLyon University Hospital, IC-HCL, Lyon University, Lyon, France.
Philippe CeruseLyon University Hospital, IC-HCL, Lyon University, Lyon, France.
Lionel BadetLyon University Hospital, IC-HCL, Lyon University, Lyon, France.
Philippe PaparelLyon University Hospital, IC-HCL, Lyon University, Lyon, France.
Alice DurandLyon University Hospital, IC-HCL, Lyon University, Lyon, France.
Marielle GuilletLyon University Hospital, IC-HCL, Lyon University, Lyon, France.
Philippe MerleLyon University Hospital, IC-HCL, Lyon University, Lyon, France.
Gaelle LescuyerLyon University Hospital, IC-HCL, Lyon University, Lyon, France.
Charles-André PhilipLyon University Hospital, IC-HCL, Lyon University, Lyon, France.
Francois DucrayLyon University Hospital, IC-HCL, Lyon University, Lyon, France.
Mathieu PiocheLyon University Hospital, IC-HCL, Lyon University, Lyon, France.
Lionel KarlinLyon University Hospital, IC-HCL, Lyon University, Lyon, France.
Jean-Christophe LifanteLyon University Hospital, IC-HCL, Lyon University, Lyon, France.
Olivier GlehenLyon University Hospital, IC-HCL, Lyon University, Lyon, France.
Pierre-Adrien BolzeLyon University Hospital, IC-HCL, Lyon University, Lyon, France.
Marion ChauvenetLyon University Hospital, IC-HCL, Lyon University, Lyon, France.
Carole Langlois-JacquesLyon University Hospital, IC-HCL, Lyon University, Lyon, France.
Fabien SubtilLyon University Hospital, IC-HCL, Lyon University, Lyon, France.
Marie PiecykLyon University Hospital, IC-HCL, Lyon University, Lyon, France.
Aurore CarrotLyon University Hospital, IC-HCL, Lyon University, Lyon, France.
Dominique JoubertProgastrin Manufacturing, Cap Sigma, 1642 rue de la Valsière, Grabels, 34790, France.
Alexandre PrieurProgastrin Manufacturing, Cap Sigma, 1642 rue de la Valsière, Grabels, 34790, France.
Berengere VireProgastrin Manufacturing, Cap Sigma, 1642 rue de la Valsière, Grabels, 34790, France.
Sara CalattiniLyon University Hospital, IC-HCL, Lyon University, Lyon, France.
Lea PayenLyon University Hospital, IC-HCL, Lyon University, Lyon, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundhPG

methodshPG

resultsBetween 2018 and 2022, a total of 506 cancer patients were enrolled in the study, with 421 assessable across 16 distinct cancer cohorts. hPG

conclusionsThis large prospective study confirms that cancer patients have significantly higher hPG

trial registrationNCT03787056.

Indexed as

Biomarkers, tumorEarly detection of CancerProspective studiesWnt signaling pathway

Identifiers

PMID40598473
PMCPMC12218953

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.