Evidence map›Paper›PMID 40598373›Full record

ArticleBMC medical informatics and decision making2025

Deep learning-based cough classification using application-recorded sounds: a transfer learning approach with VGGish.

Sanghoon Han, Yu-Rim Lee, Ji-Ho Lee, JinHee Jeon, Choongki Min, Kyungnam Kim, Donghoon Kim, Myung Pyo Kim, Young Mi Park, Uiri An and 1 more

Abstract read
In one paragraph

Article in BMC medical informatics and decision making, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Cough biomarkers for diagnosis and monitoring of respiratory disease: a systematic review.European respiratory review : an official journal of the European Respiratory Society · 2026
    Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Sanghoon HanWaycen Inc, Seoul, 06167, Republic of Korea.
Yu-Rim LeeWaycen Inc, Seoul, 06167, Republic of Korea.
Ji-Ho LeeDepartment of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju, Republic of Korea.
JinHee JeonAbler Private Clinic, Ulsan, Republic of Korea.
Choongki MinWaycen Inc, Seoul, 06167, Republic of Korea.
Kyungnam KimWaycen Inc, Seoul, 06167, Republic of Korea.
Donghoon KimDivision of Pulmonary and Allergy Medicine, Department of Internal Medicine, Chung-Ang University Hospital, Chung-Ang University College of Medicine, Seoul, Republic of Korea.
Myung Pyo KimDepartment of Pulmonology, Hyundae Hospital, Namyangju, Korea.
Young Mi ParkDepartment of Pediatrics, Gangnam Severance Hospital, Yonsei University College of Medicine, Eonjuro Gangnamgu, Seoul, Korea.
Uiri AnDepartment of Internal Medicine, Armed Forces Capital Hospital, Seongnam, Korea.
Kyoung Min MoonDivision of Pulmonary and Allergy Medicine, Department of Internal Medicine, Chung-Ang University Hospital, Chung-Ang University College of Medicine, Seoul, Republic of Korea. ml.pulmogicu@gmail.com.

Funding

Biomedical Research Institute, Chung-Ang University Hospital 2024
6 · The paper itself

Abstract

backgroundCoughing sounds contain various bio-metric information with regards to respiratory diseases that can help in the assessment of respiratory diseases. While clinicians find coughs insightful, non-experts struggle to identify abnormalities in cough sounds. Furthermore, respiratory diseases has characterized by widespread health complications and elevated mortality rates, the development of early diagnostic systems is imperative for ensuring timely intervention and improving outcomes for both clinicians and patients. Accordingly, we propose a deep learning-based model for early diagnosis. To enhance the reliability of the training data, we utilized annotations provided by multiple medical specialists. Additionally, we examined how clinical expertise and diagnostic input influence the model's generalization performance.

methodsThis study introduces a deep learning framework utilizing VGGish as a transfer learning model, enhanced with additional detection and classification networks. The detection model identifies cough events within recorded audio, and then the classification model determines whether a detected cough is normal or abnormal. Both models were trained on raw cough sound data collected via smartphones and labeled by medical experts through a rigorous inspection process.

resultsExperimental evaluations demonstrated that the cough detection model achieved an average accuracy of 0.9883, while the cough classification model attained accuracies of 0.8417, 0.8629, and 0.8662 among dataset1, 2, and 3. To enhance interpretability, we applied Grad-CAM to visualize the features that influenced the model's decision-making. Model performance was further evaluated using the area under the receiver operating characteristic curve (AUROC) and the area under the precision-recall curve (AUPRC).

conclusionsOur proposed cough classification model has the potential to assist individuals with limited access to healthcare as well as medical professionals with limited experience in diagnosing cough-related conditions. By leveraging deep learning and smartphone-recorded cough sounds, this approach aims to enhance early detection and management of respiratory diseases.

Indexed as

CoughDeep LearningRespiratory SoundsEarly DiagnosisHumansCough classificationCough detectionDeep learningMedical diagnosisRespiratory healthSmartphone-based screeningVGGish model

Identifiers

PMID40598373
PMCPMC12218819

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.