Evidence map›Paper›PMID 40598246›Full record

ArticleBMC medical informatics and decision making2025

Assessing GPT and DeepL for terminology translation in the medical domain: A comparative study on the human phenotype ontology.

Richard Noll, Alexandra Berger, Dominik Kieu, Tobias Mueller, Ferdinand O Bohmann, Angelina Müller, Svea Holtz, Philipp Stoffers, Sebastian Hoehl, Oya Guengoeze and 3 more

Abstract readComparative Study
In one paragraph

Article in BMC medical informatics and decision making, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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0cells of the map it votes in
3citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

13 authors.

Richard NollGoethe University Frankfurt, University Medicine Frankfurt, Institute of Medical Informatics, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Germany. noll@med.uni-frankfurt.de.ORCID 0000-0002-5240-8484
Alexandra BergerGoethe University Frankfurt, University Hospital Frankfurt, Frankfurt Reference Centre for Rare Diseases, Frankfurt, Germany.
Dominik KieuGoethe University Frankfurt, University Hospital Frankfurt, Frankfurt Reference Centre for Rare Diseases, Frankfurt, Germany.
Tobias MuellerFaculty of Health Sciences, University of Applied Sciences, Giessen, Germany.
Ferdinand O BohmannGoethe University Frankfurt, University Medicine Frankfurt, Institute of Medical Informatics, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Germany.
Angelina MüllerGoethe University Frankfurt, University Hospital Frankfurt, Institute of General Practice, Frankfurt, Germany.
Svea HoltzGoethe University Frankfurt, University Hospital Frankfurt, Institute of General Practice, Frankfurt, Germany.
Philipp StoffersGoethe University Frankfurt, University Medicine Frankfurt, Institute of Medical Informatics, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Germany.
Sebastian HoehlInstitute of Medical Virology, Goethe University Frankfurt, University Hospital Frankfurt, Frankfurt, Germany.
Oya GuengoezeDepartment of Internal Medicine 1, Goethe University Frankfurt, University Hospital Frankfurt, Frankfurt, Germany.
Jan-Niklas EckardtDepartment of Internal Medicine I, University Hospital Carl Gustav Carus, Technical University Dresden, Dresden, Germany.
Holger StorfGoethe University Frankfurt, University Medicine Frankfurt, Institute of Medical Informatics, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Germany.
Jannik SchaafGoethe University Frankfurt, University Medicine Frankfurt, Institute of Medical Informatics, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis paper presents a comparative study of two state-of-the-art language models, OpenAI's GPT and DeepL, in the context of terminology translation within the medical domain.

methodsThis study was conducted on the human phenotype ontology (HPO), which is used in medical research and diagnosis. Medical experts assess the performance of both models on a set of 120 translated HPO terms and their 180 synonyms, employing a 4-point Likert scale (strongly agree = 1, agree = 2, disagree = 3, strongly disagree = 4). An independent reference translation from the HeTOP database was used to validate the quality of the translation.

resultsThe average Likert rating for the selected HPO terms was 1.29 for GPT-3.5 and 1.37 for DeepL. The quality of the translations was also found to be satisfactory for multi-word terms with greater ontological depth. The comparison with HeTOP revealed a high degree of similarity between the models' translations and the reference translations.

conclusionsStatistical analysis revealed no significant differences in the mean ratings between the two models, indicating their comparable performance in terms of translation quality. The study not only illustrates the potential of machine translation but also shows incomplete coverage of translated medical terminology. This underscores the relevance of this study for cross-lingual medical research. However, the evaluation methods need to be further refined, specific translation issues need to be addressed, and the sample size needs to be increased to allow for more generalizable conclusions.

Indexed as

Biological OntologiesPhenotypeTerminology as TopicTranslatingHumansArtificial intelligenceControlled vocabularyGPTTranslations

Identifiers

PMID40598246
PMCPMC12220062

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.