Evidence map›Paper›PMID 40598135›Full record

ArticleBMC ophthalmology2025

Impact of image averaging on choroidal quantification using swept-source optical coherence tomography.

Xiaotian Wu, Yinglong Lan, Peifeng Zhang, Zhiyang Lin, Yanfeng Jiang, Shenghai Huang, Zi Jin, Yuanyuan Wang, Meixiao Shen, Sisi Chen

Abstract read
In one paragraph

Article in BMC ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xiaotian WuEye Hospital and School of Ophthalmology and Optometry, Wenzhou Medical University; Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision and Brain Health), Wenzhou, Zhejiang, 325000, China.
Yinglong LanEye Hospital and School of Ophthalmology and Optometry, Wenzhou Medical University; Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision and Brain Health), Wenzhou, Zhejiang, 325000, China.
Peifeng ZhangEye Hospital and School of Ophthalmology and Optometry, Wenzhou Medical University; Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision and Brain Health), Wenzhou, Zhejiang, 325000, China.
Zhiyang LinEye Hospital and School of Ophthalmology and Optometry, Wenzhou Medical University; Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision and Brain Health), Wenzhou, Zhejiang, 325000, China.
Yanfeng JiangEye Hospital and School of Ophthalmology and Optometry, Wenzhou Medical University; Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision and Brain Health), Wenzhou, Zhejiang, 325000, China.
Shenghai HuangEye Hospital and School of Ophthalmology and Optometry, Wenzhou Medical University; Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision and Brain Health), Wenzhou, Zhejiang, 325000, China.
Zi JinEye Hospital and School of Ophthalmology and Optometry, Wenzhou Medical University; Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision and Brain Health), Wenzhou, Zhejiang, 325000, China.
Yuanyuan WangNational Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, 325027, China.
Meixiao ShenEye Hospital and School of Ophthalmology and Optometry, Wenzhou Medical University; Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision and Brain Health), Wenzhou, Zhejiang, 325000, China. smx77@mail.eye.ac.cn.
Sisi ChenEye Hospital and School of Ophthalmology and Optometry, Wenzhou Medical University; Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision and Brain Health), Wenzhou, Zhejiang, 325000, China. chensisi@wmu.edu.cn.

Funding

Basic Research Program of Wenzhou Medical University KYYW202302Medical and Science & Technology Project of Zhejiang Province 2024KY162National Key Research and Development Program of China 2022YFC2404303Natural Science Foundation of China 82171016Wenzhou Municipal science and Technology Bureau ZY2024018
6 · The paper itself

Abstract

purposeThis study aimed to assess the impact of B-scan averaging on choroidal parameters using swept-source optical coherence tomography (SS-OCT).

methodsTwenty-two right eyes of healthy adults were scanned using SS-OCT. Each scan included five consecutive 9 mm 18-line radial scans with averaging frames of 4, 8, 16, 32, and 64. Two times of averaging were performed per eye. Choroidal images were analyzed with binarization techniques to calculate choroidal parameters, including luminal volume (LV), stromal volume (SV), choroidal vascularity index (CVI), total choroidal volume (TCV), and choroidal thickness (CT), to compare the changes and stability of these parameters under different B-scans averaging conditions.

resultsCVI showed no significant differences across averaging conditions (P > 0.05), while LV, SV, TCV, and CT differed significantly (P < 0.05). LV, TCV, and CT showed no significant differences when averaging ≥ 16 frames, whereas SV achieved stability at ≥ 8 frames.

conclusionThis study demonstrated that SS-OCT imaging of the choroid was unaffected by B-scan averaging in CVI measurements. However, LV, TCV, and CT required averaging ≥ 16 frames, while SV required averaging ≥ 8 frames for consistent results. This finding emphasizes the importance of standardized imaging protocols in clinical practice.

Indexed as

ChoroidTomography, Optical CoherenceAdultFemaleHealthy VolunteersHumansMaleMiddle AgedYoung AdultB-Scan average,, Choroidal thickness (CT)Swept-source optical coherence tomography (SS-OCT), Choroidal vascularity index (CVI)

Identifiers

PMID40598135
PMCPMC12220527

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.